product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Imatinib mesylate
catalog :
SIH-453
quantity :
20 mg
citations: 1
Reference
Okumura D, Hagino M, Yamagishi A, Kaibori Y, Munira S, Saito Y, et al. Inhibitors of the VEGF Receptor Suppress HeLa S3 Cell Proliferation via Misalignment of Chromosomes and Rotation of the Mitotic Spindle, Causing a Delay in M-Phase Progression. Int J Mol Sci. 2018;19: pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-453 image 1
Chemical structure of Imatinib mesylate (SIH-453), a BCR-ABL kinase inhibitor. CAS #: 152459-95-5. Molecular Formula: C30H35N7O4S. Molecular Weight: 589.7 g/mol.
product information
Catalog No :
SIH-453
Product Name :
Imatinib mesylate
Size :
20 mg
Description :
Kinase inhibitor
Research Area(s) :
Cell Signaling Cancer Apoptosis Cancer Growth Inhibitors Tyrosine Kinase Inhibitors
Alternative Name(s) :
4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]-phenyl]benzamide methanesulfonate, 4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)pyrimidin-2-yl]amino}phenyl)benzamide mesylate, CGP 57148, Genfatinib, Glivec, Imatinib methanesulfonate, STI-571
Category :
Small Molecules
Product Type :
Inhibitor
CAS No :
152459-95-5
Molecular Formula :
C30H35N7O4S
Molecular Weight :
589.7
Source :
Synthetic
Purity :
≥98% (HPLC)
SD File :
C29H31N7O APtclcactv07301412532D 0 0.00000 0.00000 68 72 0 0 0 0 0 0 0 0999 V2000 5.4641 5.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 6.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 1.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 -0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -2.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.7942 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -6.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.5991 4.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.7932 1.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 3.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.9282 2.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.4641 -0.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 -1.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 4.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 -0.5000 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -3.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 2.0000 -4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 -4.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 -3.5000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 0.0000 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 1.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 7.1962 5.5000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 4.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 4.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -3.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -5.0000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 2.5000 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 4.9272 5.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.3301 6.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.1042 2.4631 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 10.3312 3.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4842 3.5369 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4651 1.1900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6592 2.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.0622 0.3800 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.0010 -1.8100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 -2.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.1951 -0.1900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.5981 0.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.1350 2.6900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3291 2.6900 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.3291 4.3100 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.7321 5.1200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.6540 -1.4174 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2554 -2.1077 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7879 -2.9174 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3894 -3.6077 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.3894 -4.3923 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.7879 -5.0826 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9441 -5.0826 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3426 -4.3923 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.3426 -3.6077 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.9441 -2.9174 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.2460 -6.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 2.8660 -6.6200 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3.4860 -6.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 3 21 1 0 0 0 0 7 25 2 0 0 0 0 3 5 2 0 0 0 0 8 25 1 0 0 0 0 8 9 2 0 0 0 0 9 24 1 0 0 0 0 24 32 1 0 0 0 0 4 23 2 0 0 0 0 22 26 1 0 0 0 0 4 20 1 0 0 0 0 10 26 2 0 0 0 0 1 22 2 0 0 0 0 10 39 1 0 0 0 0 11 39 2 0 0 0 0 22 35 1 0 0 0 0 11 12 1 0 0 0 0 5 23 1 0 0 0 0 12 13 2 0 0 0 0 13 26 1 0 0 0 0 1 2 1 0 0 0 0 14 25 1 0 0 0 0 19 36 1 0 0 0 0 14 37 1 0 0 0 0 28 37 1 0 0 0 0 15 21 1 0 0 0 0 20 36 1 0 0 0 0 2 34 2 0 0 0 0 23 33 1 0 0 0 0 27 32 2 0 0 0 0 31 37 1 0 0 0 0 28 29 1 0 0 0 0 29 38 1 0 0 0 0 30 38 1 0 0 0 0 30 31 1 0 0 0 0 32 33 1 0 0 0 0 16 38 1 0 0 0 0 19 35 2 0 0 0 0 20 21 2 0 0 0 0 6 24 2 0 0 0 0 19 34 1 0 0 0 0 6 7 1 0 0 0 0 1 40 1 0 0 0 0 2 41 1 0 0 0 0 15 42 1 0 0 0 0 15 43 1 0 0 0 0 15 44 1 0 0 0 0 17 36 1 0 0 0 0 3 45 1 0 0 0 0 4 46 1 0 0 0 0 5 47 1 0 0 0 0 18 33 1 0 0 0 0 6 48 1 0 0 0 0 7 49 1 0 0 0 0 8 50 1 0 0 0 0 9 51 1 0 0 0 0 10 52 1 0 0 0 0 11 53 1 0 0 0 0 12 54 1 0 0 0 0 13 55 1 0 0 0 0 14 56 1 0 0 0 0 14 57 1 0 0 0 0 28 58 1 0 0 0 0 28 59 1 0 0 0 0 29 60 1 0 0 0 0 29 61 1 0 0 0 0 30 62 1 0 0 0 0 30 63 1 0 0 0 0 31 64 1 0 0 0 0 31 65 1 0 0 0 0 16 66 1 0 0 0 0 16 67 1 0 0 0 0 16 68 1 0 0 0 0 M END $$$$
PubChem CID :
5291
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.