product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Chloroquine diphosphate
catalog :
SIH-405
quantity :
1 g
more info or order :
StressMarq Biosciences product webpage
citations: 2
Reference
Morishige J, Yoshioka K, Nakata H, Ishimaru K, Nagata N, Tanaka T, et al. Sphingosine kinase 1 is involved in triglyceride breakdown by maintaining lysosomal integrity in brown adipocytes. J Lipid Res. 2023;64:100450 pubmed publisher
Lundquist M, Goncalves M, Loughran R, Possik E, Vijayaraghavan T, Yang A, et al. Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. Mol Cell. 2018;70:531-544.e9 pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-405 image 1
Chemical structure of Chloroquine diphosphate (SIH-405), a Autophagy inhibitor. CAS #: 50-63-5. Molecular Formula: C18H26ClN3·2H3PO4. Molecular Weight: 515.86 g/mol.
product information
Catalog No :
SIH-405
Product Name :
Chloroquine diphosphate
Size :
1 g
Description :
Autophagy inhibitor
Research Area(s) :
Cancer Autophagy
Alternative Name(s) :
N4-(7-Chloro-4-quinolinyl)-N1,N1-dimethyl-1,4-pentanediamine diphosphate salt
Category :
Small Molecules
Product Type :
Inhibitor
CAS No :
50-63-5
Molecular Formula :
C18H26ClN3·2H3PO4
Molecular Weight :
515.86
Source :
Synthetic
Purity :
>98% (HPLC); NMR (Conforms)
SD File :
C18H32ClN3O8P2 APtclcactv04251417342D 0 0.00000 0.00000 64 63 0 0 0 0 0 0 0 0999 V2000 11.4464 6.5023 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 11.4464 8.5716 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8204 7.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3524 7.0161 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8204 8.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8204 4.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9544 3.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9544 2.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.0883 1.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2223 2.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 7.9544 5.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 6.2223 0.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 5.3563 2.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.2233 5.2269 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.6864 6.5369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 12.3524 8.0578 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 8.8204 5.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 13.2165 8.5611 0.0000 Cl 0 0 0 0 0 0 0 0 0 0 0 0 7.0883 2.0369 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.6864 5.5369 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 2.8059 6.6585 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 0.0000 6.2785 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.2130 7.8715 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 1.9030 5.6025 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 2.2690 6.9685 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.5369 5.9685 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 0.9030 7.3345 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.5524 7.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 10.5524 8.0369 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0 9.6864 8.5369 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0 9.5179 11.2050 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 10.4209 12.2610 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6150 11.8810 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8279 13.4740 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.8840 12.5710 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.1519 11.5710 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 8.5179 12.9370 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0 1.4030 6.4685 0.0000 P 0 0 0 0 0 0 0 0 0 0 0 0 9.0179 12.0710 0.0000 P 0 0 0 0 0 0 0 0 0 0 0 0 11.4392 5.8823 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 11.4392 9.1916 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2835 6.7269 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 12.8882 6.7041 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2835 8.3469 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.8204 5.6569 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.0324 3.4543 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 9.4310 4.1446 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.2644 6.0739 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.4174 5.8469 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6444 5.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.7423 4.1195 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3438 3.4293 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.1664 1.9543 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 8.5649 2.6446 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.3004 0.4543 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 7.6989 1.1446 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.6208 3.0119 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.8238 3.0119 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.9123 1.0739 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6854 0.2269 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 6.5323 0.0000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.0463 2.5739 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 4.8194 1.7269 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 5.6663 1.5000 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0 28 29 2 0 0 0 0 15 28 1 0 0 0 0 1 28 1 0 0 0 0 29 30 1 0 0 0 0 2 29 1 0 0 0 0 3 15 2 0 0 0 0 15 20 1 0 0 0 0 1 4 2 0 0 0 0 5 30 2 0 0 0 0 2 16 2 0 0 0 0 17 20 1 0 0 0 0 16 18 1 0 0 0 0 6 17 1 0 0 0 0 11 17 1 0 0 0 0 6 7 1 0 0 0 0 7 8 1 0 0 0 0 8 19 1 0 0 0 0 9 19 1 0 0 0 0 10 19 1 0 0 0 0 9 12 1 0 0 0 0 10 13 1 0 0 0 0 25 38 1 0 0 0 0 26 38 1 0 0 0 0 27 38 1 0 0 0 0 24 38 2 0 0 0 0 35 39 1 0 0 0 0 36 39 1 0 0 0 0 37 39 1 0 0 0 0 31 39 2 0 0 0 0 3 5 1 0 0 0 0 4 16 1 0 0 0 0 1 40 1 0 0 0 0 2 41 1 0 0 0 0 3 42 1 0 0 0 0 14 20 1 0 0 0 0 4 43 1 0 0 0 0 5 44 1 0 0 0 0 17 45 1 0 0 0 0 6 46 1 0 0 0 0 6 47 1 0 0 0 0 11 48 1 0 0 0 0 11 49 1 0 0 0 0 11 50 1 0 0 0 0 7 51 1 0 0 0 0 7 52 1 0 0 0 0 8 53 1 0 0 0 0 8 54 1 0 0 0 0 9 55 1 0 0 0 0 9 56 1 0 0 0 0 10 57 1 0 0 0 0 10 58 1 0 0 0 0 12 59 1 0 0 0 0 12 60 1 0 0 0 0 12 61 1 0 0 0 0 13 62 1 0 0 0 0 13 63 1 0 0 0 0 13 64 1 0 0 0 0 21 25 1 0 0 0 0 22 26 1 0 0 0 0 23 27 1 0 0 0 0 32 35 1 0 0 0 0 33 36 1 0 0 0 0 34 37 1 0 0 0 0 M END $$$$
PubChem CID :
64927
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.