product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Deguelin
catalog :
SIH-251
quantity :
10 mg
citations: 4
Reference
Yuki R, Ikeda Y, Yasutake R, Saito Y, Nakayama Y. SH2D4A promotes centrosome maturation to support spindle microtubule formation and mitotic progression. Sci Rep. 2023;13:2067 pubmed publisher
Kaibori Y, Saito Y, Nakayama Y. EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity. FASEB J. 2019;33:5334-5349 pubmed publisher
Eng J, Reed C, Kokolus K, Pitoniak R, Utley A, Bucsek M, et al. Housing temperature-induced stress drives therapeutic resistance in murine tumour models through β2-adrenergic receptor activation. Nat Commun. 2015;6:6426 pubmed publisher
Kuga T, Nie H, Kazami T, Satoh M, Matsushita K, Nomura F, et al. Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. Oncogenesis. 2014;3:e94 pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-251 image 1
Chemical structure of Deguelin (SIH-251), a Akt inhibitor. CAS #: 522-17-8. Molecular Formula: C23H22O6. Molecular Weight: 394.42 g/mol.
product information
Catalog No :
SIH-251
Product Name :
Deguelin
Size :
10 mg
Description :
Akt inhibitor
Research Area(s) :
Cancer Apoptosis
Alternative Name(s) :
(7aS,13aS)-9,10-Dimethoxy-3,3-dimethyl-13,13a-dihydro-3H-chromeno[3,4-b]pyrano[2,3-h]chromen-7(7aH)-one
Category :
Small Molecules
Product Type :
Inducer
CAS No :
522-17-8
Molecular Formula :
C23H22O6
Molecular Weight :
394.42
Source :
Synthetic
Purity :
>98%
PubChem CID :
107935
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.