product summary
Loading...
company name :
StressMarq Biosciences
product type :
chemical
product name :
Necrostatin
catalog :
SIH-213-10MG
quantity :
10 mg
price :
68 USD
more info or order :
StressMarq Biosciences product webpage
citations: 3
Reference
Langemann D, Trochimiuk M, Appl B, Hundsdoerfer P, Reinshagen K, Eschenburg G. Sensitization of neuroblastoma for vincristine-induced apoptosis by Smac mimetic LCL161 is attended by G2 cell cycle arrest but is independent of NF?B, RIP1 and TNF-?. Oncotarget. 2017;8:87763-87772 pubmed publisher
Bittner S, Knoll G, Ehrenschwender M. Death receptor 3 mediates necroptotic cell death. Cell Mol Life Sci. 2017;74:543-554 pubmed publisher
Bullenkamp J, Raulf N, Ayaz B, Walczak H, Kulms D, Odell E, et al. Bortezomib sensitises TRAIL-resistant HPV-positive head and neck cancer cells to TRAIL through a caspase-dependent, E6-independent mechanism. Cell Death Dis. 2014;5:e1489 pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-213-10MG image 1
Chemical structure of Necrostatin (SIH-213), a Inhibits necroptosis. CAS #: 4311-88-0. Molecular Formula: C13H13N3OS . Molecular Weight: 259.33 g/mol.
product information
Catalog No :
SIH-213-10MG
Product Name :
Necrostatin
Category :
Small Molecules
Product Type :
Inhibitor
Size :
10 mg
List Price USD :
68 USD
Description :
Necroptosis inhibitor
Alternative Name(s) :
5-(1H-Indol-3-ylmethyl)-3-methyl-2-thioxo-4-imidazolidinone, Necrostatin-1
CAS No :
4311-88-0
MolecularFormula :
C13H13N3OS
Molecular Weight :
259.33
Source :
Synthetic
Purity :
>98%
SMILES :
CN1C(=O)C(NC1=S)CC2=CNC3=CC=CC=C32
InChI :
InChI=1S/C13H13N3OS/c1-16-12(17)11(15-13(16)18)6-8-7-14-10-5-3-2-4-9(8)10/h2-5,7,11,14H,6H2,1H3,(H,15,18)
InChIKey :
TXUWMXQFNYDOEZ-UHFFFAOYSA-N
PubChem CID :
2828334
more info or order :
StressMarq Biosciences product webpage
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.