product summary
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company name :
StressMarq Biosciences
product type :
chemical
product name :
Geldanamycin
catalog :
SIH-111
quantity :
SIH-111
citations: 3
Reference
Dieudé M, Bell C, Turgeon J, Beillevaire D, Pomerleau L, Yang B, et al. The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection. Sci Transl Med. 2015;7:318ra200 pubmed publisher
Mori M, Hitora T, Nakamura O, Yamagami Y, Horie R, Nishimura H, et al. Hsp90 inhibitor induces autophagy and apoptosis in osteosarcoma cells. Int J Oncol. 2015;46:47-54 pubmed publisher
Cha J, St Louis K, Tradewell M, Gentil B, Minotti S, Jaffer Z, et al. A novel small molecule HSP90 inhibitor, NXD30001, differentially induces heat shock proteins in nervous tissue in culture and in vivo. Cell Stress Chaperones. 2014;19:421-35 pubmed publisher
image
image 1 :
StressMarq Biosciences SIH-111 image 1
Chemical structure of Geldanamycin (SIH-111), a Hsp90 inhibitor. CAS #: 30562-34-6. Molecular Formula: C29H40N2O9. Molecular Weight: 560.6 g/mol.
product information
Catalog No :
SIH-111
Product Name :
Geldanamycin
Size 1 :
1 mg
Size 2 :
5mg
Description :
Hsp90 inhibitor
Research Area(s) :
Cancer Heat Shock
Alternative Name(s) :
(4E,6Z,8S,9S,10E,12S,13R,14S,16R)-13-hydroxy-8,14,19-trimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1] docosa-1(21),4,6,10,18-pentaen-9-yl carbamate
Category :
Small Molecules
Product Type :
Inhibitor
CAS No :
30562-34-6
MolecularFormula :
C29H40N2O9
Molecular Weight :
560.6
Source :
Produced by fermentation
Purity :
>95%
PubChem CID :
5288382
company information
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com
1-250-294-9065
headquarters: canada
StressMarq Biosciences Inc. is a bioreagents company producing high-quality antibodies, antibody conjugates, proteins, assay kits, and small molecules for the life sciences.
With over 17,000 products, we offer a wide range of products for scientists in cancer, neuroscience, epigenetics, cell signalling, and cellular stress research areas.
Based in Victoria, BC, with a small but dedicated group of scientists, StressMarq provides highly-validated products that are sold with our quality guarantee, and supported by our years of scientific expertise. Our products are available in over 50 countries through our extensive distributor network.
StressMarq draws on scientific excellence from around the globe. We strive to partner with academic or for-profit institutions through licensing agreements to bring cutting-edge research tools to the scientific community.