product summary
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-LC3A antibody
catalog :
STJ97755
quantity :
100μl
price :
150 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5G10

The same clone is also sold as:
reactivity :
human
application :
western blot, immunohistochemistry - paraffin section
more info or order :
St John's Laboratory product webpage
image
image 1 :
St John's Laboratory STJ97755 image 1
Western blot (WB) analysis of LC3A Mouse Monoclonal Antibody(5G10).
product information
Catalog Number :
STJ97755
Product Name :
Anti-LC3A antibody
Product Type :
Primary Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Clone Name :
5G10
Isotype :
IgG1
Size :
100μl
List Price :
150 USD
Product Description :
LC3A is a protein encoded by the MAP1LC3A gene which is approximately 14,3 kD. LC3A is localised to the cytoplasm, cytoskeleton and autophagosome. It is involved in pathways such as the autophagy pathway, pink/parkin mediated mitophagy, ferroptosis, cellular senescence and pathways affecting insulin-like growth factor-Akt signalling. MAP1A and MAP1B fall under the LC3A protein. They are microtubule-associated proteins that mediate the physical interactions between microtubules and components of the cytoskeleton. LC3A is most abundant in heart, brain, liver, skeletal muscle and testis but absent in thymus and peripheral blood leukocytes. Mutations in the LC3A gene may result in Nasu-Hakola disease , lacrimal gland adenocarcinoma and leber congenital amaurosis. STJ97755 was developed from clone 5G10. It was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous levels of LC3A.
CrossReactivity :
Human, Mouse, Rat
ALTnames :
MAP1LC3A antibody, Microtubule-associated proteins 1A/1B light chain 3A antibody, Autophagy-related protein LC3 A antibody, Autophagy-related ubiquitin-like modifier LC3 A antibody, MAP1 light chain 3-like protein 1 antibody, MAP1A/MAP1B light chain 3 A antibody, MAP1A/MAP1B LC3 A antibody, Microtubule-associated protein 1 light chain 3 alpha antibody
Immunogen :
synthetic peptide derived from LC3A
Localization :
Cytoplasm, cytoskeleton. Endomembrane system; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome Note=LC3-II binds to the autophagic membranes.
Specificity :
LC3A Mouse Monoclonal Antibody (5G10) detects endogenous levels of LC3A
Purity :
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB, IHC-p
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
more info or order :
St John's Laboratory product webpage
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK