Anti-Talin-1 antibody | St John's Laboratory STJ97271 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-Talin-1 antibody

catalog :

STJ97271

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of K562 cells using Talin-1 Polyclonal Antibody.

product information

Catalog Number :

STJ97271

Product Name :

Anti-Talin-1 antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

TLN1 antibody, KIAA1027 antibody, TLN antibody, Talin-1 antibody

Immunogen :

Synthesized peptide derived from human Talin-1.

Epitope :

C-terminal

Localization :

Cell projection, ruffle membrane Cytoplasm, cytoskeleton Cell surface Cell junction, focal adhesion Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).

Specificity :

Talin-1 Polyclonal Antibody detects endogenous levels of Talin-1 protein.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IHC-p, ELISA, IF

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage