product summary
Loading...
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-Glucocorticoid receptor antibody
catalog :
STJ97101
quantity :
100μl
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
more info or order :
image
image 1 :
Western Blot (WB) analysis of 1) HeLa, 2) Jurkat, 3) HepG2, 4) Mouse Liver tissue, 5) Rat Brain tissue, diluted at 1:2000.
product information
Catalog Number :
STJ97101
Product Name :
Anti-Glucocorticoid receptor antibody
Product Type :
Primary Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100μl
List Price :
150 USD
Product Description :
Glucocorticoid receptor is a protein encoded by the NR3C1 gene which is approximately 85,6 kDa. The glucocorticoid receptor is localised to the cytoplasm, mitochondrion and nucleus. It is involved in PEDF induced signalling, gene expression and the nuclear receptor transcription pathway. It is a protein which can function both as a transcription factor that binds to glucocorticoid response elements to activate their transcription, and as a regulator of other transcription factors. The glucocorticoid receptor is widely expressed. Mutations in the NR3C1 gene may result in glucocorticoid resistance. STJ97101 was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen. This antibody detects endogenous GR proteins.
CrossReactivity :
Human, Mouse, Rat
ALTnames :
NR3C1 antibody, GRL antibody, Glucocorticoid receptor antibody, GR antibody, Nuclear receptor subfamily 3 group C member 1 antibody
Immunogen :
Recombinant Protein
Localization :
Isoform Alpha: Cytoplasm Nucleus Mitochondrion Cytoplasm, cytoskeleton, spindle Cytoplasm, cytoskeleton, microtubule organizing center, centrosome Note=After ligand activation, translocates from the cytoplasm to the nucleus. ; Isoform Beta: Nucleus Cytoplasm Note=Expressed predominantly in the nucleus with some expression also detected in the cytoplasm. ; Isoform Alpha-B: Nucleus Cytoplasm Note=After ligand activation, translocates from the cytoplasm to the nucleus.
Specificity :
The antibody detects endogenous GR proteins.
Purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Application Summary :
WB
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
more info or order :
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com+44 (0)2072322321
headquarters: UK