Anti-β-tubulin antibody | St John's Laboratory STJ97037 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-β-tubulin antibody

catalog :

STJ97037

quantity :

100μl

price :

150 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

M7

The same clone is also sold as:

Abnova: MAB15255

reactivity :

human

application :

western blot, immunocytochemistry

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of 1) HeLa, 2) Mouse Brain tissue, 3) Rat Brain tissue, diluted at 1:5000.

product information

Catalog Number :

STJ97037

Product Name :

Anti-β-tubulin antibody

Product Type :

Primary Antibody

Host Species :

Mouse

Clonality :

Monoclonal

Conjugation :

Unconjugated

Clone Name :

Isotype :

IgG1

Size :

100μl

List Price :

150 USD

Product Description :

Beta tubulin is a protein encoded by the tubb gene which is approximately 49,7 kDa. Beta tubulin is localised to the cytoskeleton and cytoplasm. It is involved in the regulation of PLK1 activity at G2/M transition, development of Slit-Robo signalling, the innate immune system, cell cycle and organelle biogenesis and maintenance. Beta tubulin contains a highly acidic C-terminal region which can bind cations such as calcium. Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain and forms part of the cytoskeleton. Beta tubulin is ubiquitously expressed in the spleen, thymus and immature brain. Mutations in the tubb gene result in complex cortical dysplasia with other brain malformations. Mutations can also cause congenital symmetric circumferential, an autosomal dominant disease which results in multiple rings of folded skin mostly affecting the limbs. STJ97037 was developed from clone M7. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. The antibody detects endogenous beta tubulin.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

TUBB3 antibody, TUBB4 antibody, Tubulin beta-3 chain antibody, Tubulin beta-4 chain antibody, Tubulin beta-III antibody

Immunogen :

Synthetic Peptide

Epitope :

C-term

Localization :

Cytoplasm, cytoskeleton.

Specificity :

The antibody detects endogenousβ-tubulin protein.

Purity :

The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IF

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage