product summary
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-beta actin antibody
catalog :
STJ96941
quantity :
100μl
price :
150 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
5B7

The same clone is also sold as:
reactivity :
human
application :
western blot
more info or order :
St John's Laboratory product webpage
product information
Catalog Number :
STJ96941
Product Name :
Anti-beta actin antibody
Product Type :
Primary Antibody
Host Species :
Mouse
Clonality :
Monoclonal
Conjugation :
Unconjugated
Clone Name :
5B7
Isotype :
IgG1
Size :
100μl
List Price :
150 USD
Product Description :
Beta actin is a protein encoded by the ACTB gene which is approximately 41,7 kDa. Beta actin is localised to the cytoplasm. It is involved in pathways such as blood-brain barrier and immune cell transmigration, regulation of actin cytoskeleton by Rho GTPases and development Slit-Robo signalling. This protein falls under the actin family. There are 3 main groups of actin isoforms in vertebrates namely, alpha, beta and gamma actins. Beta actin is a highly conserved proteins that is involved in various types of internal cell motility and are the major constituent of microfilaments. Beta actin is ubiquitously expressed in all eukaryotic cells. Mutations in the ACTB gene result in a form of juvenile-onset dystonia, which is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. Baraitser-Winter syndrome 1 is another disease that can occur due to mutations. This is rare developmental disorder that causes postnatal short stature and microcephaly, intellectual disability, seizures, and hearing loss. STJ96941 was developed from clone 5B7. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody binds endogenous beta actin.
CrossReactivity :
Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit
ALTnames :
ACTB antibody, Actin, cytoplasmic 1 antibody, Beta-actin antibody, Actin, cytoplasmic 1, N-terminally processed antibody
Immunogen :
Synthetic Peptide
Epitope :
C-term
Localization :
Cytoplasm, cytoskeleton Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Specificity :
The antibody detects endogenous β-actin protein.
Purity :
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
more info or order :
St John's Laboratory product webpage
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK