Anti-SUMO-1 antibody | St John's Laboratory STJ95835 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-SUMO-1 antibody

catalog :

STJ95835

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of specific cells using SUMO-1 Polyclonal Antibody.

product information

Catalog Number :

STJ95835

Product Name :

Anti-SUMO-1 antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

SUMO-1 is a protein encoded by the SUMO1 gene which is approximately 11,6 kDa. SUMO-1 is localised to the nuclear membrane and nucelus. It is involved in SUMOylation, DNA double-strand break repair, transcription-coupled nucleotide excision repair and interferon gamma signalling. This protein falls under the SUMO protein family. It functions similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. This protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. SUMO-1 is expressed in the cells of the nervous system, liver, lung, kidney and blood. Mutations in the SUMO1 gene result in disease such as non-syndromic orofacial cleft 10 which is a birth defect exhibiting cleft lips which can range in severity and can occur on one or both sides. TJ95835 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody binds endogenous SUMO-1.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

SUMO1 antibody, SMT3C antibody, SMT3H3 antibody, UBL1 antibody, OK/SW-cl.43 antibody, Small ubiquitin-related modifier 1 antibody, SUMO-1 antibody, GAP-modifying protein 1 antibody, GMP1 antibody, SMT3 homolog 3 antibody, Sentrin antibody, Ubiquitin-homology domain protein PIC1 antibody, Ubiquitin-like protein SMT3C antibody, Smt3C antibody, Ubiquitin-like protein UBL1 antibody

Immunogen :

Synthesized peptide derived from human SUMO-1

Epitope :

1-80 aa, N-terminal

Localization :

Nucleus membrane. Nucleus speckle. Cytoplasm. Nucleus, PML body. Cell membrane Nucleus Note=Recruited by BCL11A into the nuclear body. In the presence of ZFHX3, sequesterd to nuclear body (NB)-like dots in the nucleus some of which overlap or closely associate with PML body.

Specificity :

SUMO-1 Polyclonal Antibody detects endogenous levels of SUMO-1 protein.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IHC-p, IF, ELISA

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage