Anti-p63 antibody | St John's Laboratory STJ94912 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-p63 antibody

catalog :

STJ94912

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

St John's Laboratory product webpage

product information

Catalog Number :

STJ94912

Product Name :

Anti-p63 antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

P63 is a protein encoded by the TP63 gene which is approximately 76,8 kDa. P63 is localised to the nucleus and is involved in the regulation of transcription of cell death genes, activation of BH3-only proteins, regulation of TP53 activity and gene expression. This protein falls under the p53 family of transcription factors. p63 acts as a sequence specific DNA binding transcriptional activator or repressor. By interacting with TP73/p73 it may also be required for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. It is expressed in the skin, muscle, blood and lungs. Mutations in the TP63 gene can result in ectrodactyly and Rap-Hodgkin syndrome. STJ94912 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p63 protein.

CrossReactivity :

Human, Mouse, Rat, Monkey

ALTnames :

TP63 antibody, KET antibody, P63 antibody, P73H antibody, P73L antibody, TP73L antibody, Tumor protein 63 antibody, p63 antibody, Chronic ulcerative stomatitis protein antibody, CUSP antibody, Keratinocyte transcription factor KET antibody, Transformation-related protein 63 antibody, TP63 antibody, Tumor protein p73-like antibody, p73L antibody, p40 antibody, p51 antibody

Immunogen :

Synthesized peptide derived from human p63

Epitope :

600-680 aa, C-terminal

Localization :

Nucleus

Specificity :

p63 Polyclonal Antibody detects endogenous levels of p63 protein.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IHC-p, IF, ELISA

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage