product summary
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company name :
St John's Laboratory
product type :
antibody
product name :
Anti-Mfn2 antibody
catalog :
STJ94105
quantity :
100μl
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry - paraffin section
citations: 1
Reference
Padder R, Bhat Z, Ahmad Z, Singh N, Husain M. DRP1 Promotes BRAFV600E-Driven Tumor Progression and Metabolic Reprogramming in Colorectal Cancer. Front Oncol. 2020;10:592130 pubmed publisher
product information
Catalog Number :
STJ94105
Product Name :
Anti-Mfn2 antibody
Product Type :
Primary Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100μl
Product Description :
Mfn2 is a protein encoded by the MFN2 gene which is approximately 86,4 kDa. Mfn2 is localised to the mitochondrion outer membrane. It is involved in pink/parkin mediated mitophagy, toll-like receptor signalling pathways and glucose / energy metabolism. It is a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. Mfn2 is ubiquitously expressed at low levels. Mutations in the MFN2 gene may result in Charcot-Marie-Tooth disease. STJ94105 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Mfn2 protein.
CrossReactivity :
Human, Mouse, Rat
ALTnames :
MFN2 antibody, CPRP1 antibody, KIAA0214 antibody, Mitofusin-2 antibody, Transmembrane GTPase MFN2 antibody
Immunogen :
Synthesized peptide derived from human Mfn2.
Epitope :
Internal
Localization :
Mitochondrion outer membrane Note=Colocalizes with BAX during apoptosis.
Specificity :
Mfn2 Polyclonal Antibody detects endogenous levels of Mfn2 protein.
Purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB, IHC-p, ELISA
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
http://www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK