product summary
Loading...
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-Lamin B1 antibody
catalog :
STJ93887
quantity :
100μl
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section
more info or order :
St John's Laboratory product webpage
image
image 1 :
St John's Laboratory STJ93887 image 1
Western blot (WB) analysis of Lamin B1 Polyclonal Antibody.
product information
Catalog Number :
STJ93887
Product Name :
Anti-Lamin B1 antibody
Product Type :
Primary Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100μl
List Price :
150 USD
Product Description :
Lamin B1 is a protein encoded by the LMNB1 gene which is approximately 66,4 kDa. Lamin B1 is localised to the nuclear inner membrane. It is involved in the apoptosis and survival caspase cascade , mitotic cell cycle, granzyme pathway and CDK-mediated phosphorylatin. It is one of the two B-type lamin proteins and is a component of the nuclear lamina. It is thought to provide a framework for the nuclear envelope and may also interact with chromatin. Lamin B1 is expressed in the liver, nervous system, eye, heart and intestine. Mutations in the LMNB1 gene result in autosomal dominant, adult-onset leukodystrophy. STJ93887 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Lamin B1 protein.
CrossReactivity :
Human, Mouse, Rat
ALTnames :
LMNB1 antibody, LMN2 antibody, LMNB antibody, Lamin-B1 antibody
Immunogen :
Synthesized peptide derived from human Lamin B1.
Epitope :
N-terminal
Localization :
Nucleus inner membrane; Lipid-anchor; Nucleoplasmic side.
Specificity :
Lamin B1 Polyclonal Antibody detects endogenous levels of Lamin B1 protein.
Purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB, IHC-p, ELISA, IF
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
more info or order :
St John's Laboratory product webpage
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK