product summary
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-IFN-γRα antibody
catalog :
STJ93645
quantity :
100μl
price :
150 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section
product information
Catalog Number :
STJ93645
Product Name :
Anti-IFN-γRα antibody
Product Type :
Primary Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100μl
List Price :
150 USD
Product Description :
IFN-γRα is a protein encoded by the IFNGR1 gene which is approximately 54,4 kDa. IFN-γRα is localised to the cell membrane and is involved in influenza A, Th17 cell differentiation, interferon gamma signalling, toxoplasmosis and type I interferon signalling pathways. It is a ligand-binding chain of the gamma interferon receptor which also includes IFNGR2. It associates with IFNGR2 to form a receptor for the cytokine interferon gamma. It is also associated with susceptibility to Helicobacter pylori infection. IFN-γRα is expressed in the nervous system, blood, spleen, lymph node and intestine. Mutations in the IFNGR1 gene result in immunodeficiency 27A and B. STJ93645 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of IFN-γRα protein.
CrossReactivity :
Human, Mouse, Rat, Monkey
ALTnames :
IFNGR1 antibody, Interferon gamma receptor 1 antibody, IFN-gamma receptor 1 antibody, IFN-gamma-R1 antibody, CDw119 antibody, Interferon gamma receptor alpha-chain antibody, IFN-gamma-R-alpha antibody, CD antigen CD119 antibody
Immunogen :
Synthesized peptide derived from human IFN-γRα around the non-phosphorylation site of Y457.
Epitope :
400-480 aa
Localization :
Cell membrane
Specificity :
IFN-γRα Polyclonal Antibody detects endogenous levels of IFN-γRα protein.
Purity :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Buffer :
Liquid in PBS containing 50% glycerol, 0.5% BSA
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB, IHC-p, IF, ELISA
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK