Anti-Enolase antibody | St John's Laboratory STJ92926 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-Enolase antibody

catalog :

STJ92926

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of specific cells using Enolase Polyclonal Antibody.

product information

Catalog Number :

STJ92926

Product Name :

Anti-Enolase antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

Enolase is a protein encoded by the ENO2 gene which is approximately 47,2 kDa. Enolase is localised to the cytoplasm and cell membrane and is involved in glucose metabolism, carbon metabolism, HIF-1 signalling pathway and de-adenylation-dependent mRNA decay. It is one of the three enolase isoenzymes found in mammals. It has neurotrophic and neuroprotective properties on number of central nervous system neurons. It binds to cultured neocortical neurons in the presence of calcium and promotes cell survival. The enolase alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons. Mutations in the ENO2 gene can result in granular cell tumors, pediatric ovarian dysgerminoma and olfactory neuroblastoma. The antibody STJ92926 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Enolase protein.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

ENO2 antibody, Gamma-enolase antibody, 2-phospho-D-glycerate hydro-lyase antibody, Enolase 2 antibody, Neural enolase antibody, Neuron-specific enolase antibody, NSE antibody

Immunogen :

Synthesized peptide derived from human Enolase

Epitope :

340-420 aa, C-terminal

Localization :

Cytoplasm Cell membrane Note=Can translocate to the plasma membrane in either the homodimeric (alpha/alpha) or heterodimeric (alpha/gamma) form.

Specificity :

Enolase Polyclonal Antibody detects endogenous levels of Enolase protein.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IHC-p, IF, ELISA

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage