St John's Laboratory

antibody

Anti-Phospho-Synapsin I (S605) antibody

STJ91309

100μl

150 USD

polyclonal

rabbit

nonconjugated

phosphorylated

ELISA, immunocytochemistry, immunohistochemistry - paraffin section

STJ91309

Anti-Phospho-Synapsin I (S605) antibody

Primary Antibody

Rabbit

Polyclonal

Unconjugated

phosphorylated

IgG

100μl

150 USD

Synapsin I is a protein encoded by the SYN1 gene which is approximately 74,1 kDa. Synapsin I is localised to the Golgi apparatus and cell junction. It is involved in the neurotransmitter release cycle, MAPK-Erk pathway and the brain-derived neurotrophic factor signalling pathway. It is a neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton and is believed to function in the regulation of neurotransmitter release. It forms a complex with NOS1 and CAPON proteins and is necessary for specific nitric-oxide functions at a presynaptic level. Synapsin I is expressed in the nervous system, adrenal gland and eye. Mutations in the SYN1 gene may result in X-linked epilepsy. STJ91309 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous synapsin I protein which only binds about S605 when S605 is phosphorylated.

Human, Mouse, Rat

SYN1 antibody, Synapsin-1 antibody, Brain protein 4.1 antibody, Synapsin I antibody, Phospho-Synapsin I (S605) antibody

Synthesized peptide derived from human Synapsin I around the phosphorylation site of S605.

550-630 aa

Cell junction, synapse. Golgi apparatus

Phospho-Synapsin I (S605) Polyclonal Antibody detects endogenous levels of Synapsin I protein only when phosphorylated at S605.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Liquid in PBS containing 50% glycerol, 0.5% BSA

0.02% sodium azide

1 mg/ml

IHC-p, IF, ELISA

Store at -20°C, and avoid repeat freeze-thaw cycles.