Anti-Phospho-CRMP-2 (T509) antibody | St John's Laboratory STJ90974 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-Phospho-CRMP-2 (T509) antibody

catalog :

STJ90974

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry - paraffin section

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of JK cells using Phospho-CRMP-2 (T509) Polyclonal Antibody.

product information

Catalog Number :

STJ90974

Product Name :

Anti-Phospho-CRMP-2 (T509) antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Antigen Modification :

phosphorylated

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

CRMP-2 is a protein encoded by the DPYSL2 gene which is approximately 62,2 kDa. CRMP-2 is localised to the cytoplasm and cytosol. It is involved in developmental biology, semaphorin interactions, development slit-robo signalling, axon guidance and cytoskeletal signalling. This protein falls under the collapsin response mediator protein family. It plays a role in neuronal development and polarity, as well as in axon growth and guidance, neuronal growth cone collapse and cell migration. CRMP-2 is ubiquitously expressed. Mutations in the DPYSL2 gene may result in Alzheimer disease. STJ90974 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.This primary antibody specifically binds to endogenous CRMP-2 protein which only binds about T509 when T509 is phosphorylated.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

DPYSL2 antibody, CRMP2 antibody, ULIP2 antibody, Dihydropyrimidinase-related protein 2 antibody, DRP-2 antibody, Collapsin response mediator protein 2 antibody, CRMP-2 antibody, N2A3 antibody, Unc-33-like phosphoprotein 2 antibody, ULIP-2 antibody, Phospho-CRMP-2 (T509) antibody

Immunogen :

Synthesized peptide derived from human CRMP-2 around the phosphorylation site of T509.

Epitope :

450-530 aa

Localization :

Cytoplasm, cytosol Cytoplasm, cytoskeleton Membrane Note=Tightly but non-covalently associated with membranes.

Specificity :

Phospho-CRMP-2 (T509) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at T509.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, IHC-p, ELISA

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage