Anti-Cleaved-Caspase-3 p17 (D175) antibody | St John's Laboratory STJ90026 product information

product summary

company name :

St John's Laboratory

product type :

antibody

product name :

Anti-Cleaved-Caspase-3 p17 (D175) antibody

catalog :

STJ90026

quantity :

100μl

price :

150 USD

clonality :

polyclonal

host :

rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA

more info or order :

St John's Laboratory product webpage

image

image 1 :

Western Blot (WB) analysis of HepG2 cells using polyclonal Anti-Cleaved-Caspase-3 p17 (D175) Antibody (STJ90026).

product information

Catalog Number :

STJ90026

Product Name :

Anti-Cleaved-Caspase-3 p17 (D175) antibody

Product Type :

Primary Antibody

Host Species :

Rabbit

Clonality :

Polyclonal

Conjugation :

Unconjugated

Antigen Modification :

Cleaved

Isotype :

IgG

Size :

100μl

List Price :

150 USD

Product Description :

Caspase-3 p17 is a protein encoded by the CASP3 gene which is approximately 31,6 kDa. Caspase-3 p17 is localised to the cytoplasm. It is involved in the TNFR1 pathway, apoptosis modulation and signalling and respiratory electron transport. This protein falls under the cysteine-aspartic acid protease family. It is a sequential activatior of caspases and plays a central role in the execution-phase of cell apoptosis. Caspase-3 p17 is highly expressed in lung, spleen, heart, liver and kidney. Mutations in the CASP3 gene may result in bladder urothelial carcinoma and primary effusion lymphoma. STJ90026 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of fragment of activated Caspase-3 p17 protein resulting from cleavage adjacent to D175.

CrossReactivity :

Human, Mouse, Rat

ALTnames :

CASP3 antibody, CPP32 antibody, Caspase-3 antibody, CASP-3 antibody, Apopain antibody, Cysteine protease CPP32 antibody, CPP-32 antibody, Protein Yama antibody, SREBP cleavage activity 1 antibody, SCA-1 antibody, Caspase-3 subunit p17 antibody, Caspase-3 subunit p12 antibody, Cleaved-Caspase-3 p17 (D175) antibody

Immunogen :

Synthesized peptide derived from human Caspase-3 p17

Epitope :

100-180 aa, Internal

Localization :

Cytoplasm

Specificity :

Cleaved-Caspase-3 p17 (D175) Polyclonal Antibody detects endogenous levels of fragment of activated Caspase-3 p17 protein resulting from cleavage adjacent to D175.

Purity :

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Buffer :

Liquid in PBS containing 50% glycerol, 0.5% BSA

Preservative :

0.02% sodium azide

Concentration :

1 mg/ml

Application Summary :

WB, ELISA

Storage :

Store at -20°C, and avoid repeat freeze-thaw cycles.

more info or order :

St John's Laboratory product webpage