product summary
company name :
St John's Laboratory
product type :
antibody
product name :
Anti-CHRNG antibody
catalog :
STJ110194
quantity :
100μl
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot
product information
Catalog Number :
STJ110194
Product Name :
Anti-CHRNG antibody
Product Type :
Primary Antibody
Host Species :
Rabbit
Clonality :
Polyclonal
Conjugation :
Unconjugated
Isotype :
IgG
Size :
100μl
List Price :
230 USD
Product Description :
The mammalian muscle-type acetylcholine receptor is a transmembrane pentameric glycoprotein with two alpha subunits, one beta, one delta, and one epsilon (in adult skeletal muscle) or gamma (in fetal and denervated muscle) subunit. This gene, which encodes the gamma subunit, is expressed prior to the thirty-third week of gestation in humans. The gamma subunit of the acetylcholine receptor plays a role in neuromuscular organogenesis and ligand binding and disruption of gamma subunit expression prevents the correct localization of the receptor in cell membranes. Mutations in this gene cause Escobar syndrome and a lethal form of multiple pterygium syndrome. Muscle-type acetylcholine receptor is the major antigen in the autoimmune disease myasthenia gravis.
CrossReactivity :
Human, Mouse, Rat
ALTnames :
CHRNG antibody, ACHRG antibody, Acetylcholine receptor subunit gamma antibody
Immunogen :
Recombinant peptide derived from human CHRNG.
Localization :
Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Purity :
Anti-CHRNG antibody was affinity purified using immunizing peptide
Buffer :
PBS, 50% glycerol, pH7.4
Preservative :
0.02% sodium azide
Concentration :
1 mg/ml
Application Summary :
WB
Storage :
Store at -20°C, and avoid repeat freeze-thaw cycles.
company information
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
+44 (0)2072322321
headquarters: UK