AMPK (A1/B1/G1), Active | Sino Biological P47-10H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

AMPK (A1/B1/G1), Active

catalog :

P47-10H

quantity :

10 µg

price :

658 USD

more info or order :

Sino Biological product webpage

citations: 11

Reference
Yin J, Wang X, Ge X, Ding F, Shi Z, Ge Z, et al. Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for driving chemoresistance of glioblastomas. Nat Commun. 2023;14:5913 pubmed publisher
Liu R, Lee J, Li J, Yu R, Tan L, Xia Y, et al. Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets. Mol Cell. 2021;81:2722-2735.e9 pubmed publisher
Matzinger M, Fischhuber K, Pölöske D, Mechtler K, Heiss E. AMPK leads to phosphorylation of the transcription factor Nrf2, tuning transactivation of selected target genes. Redox Biol. 2019;29:101393 pubmed publisher
Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed publisher
Liu X, Chen Z, Han Z, Liu Y, Wu X, Peng Y, et al. AMPK-mediated degradation of Nav1.5 through autophagy. FASEB J. 2019;33:5366-5376 pubmed publisher
Das B, Neilsen B, Fisher K, Gehring D, Hu Y, Volle D, et al. A Functional Signature Ontology (FUSION) screen detects an AMPK inhibitor with selective toxicity toward human colon tumor cells. Sci Rep. 2018;8:3770 pubmed publisher
Jin L, Chun J, Pan C, Kumar A, Zhang G, Ha Y, et al. The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer. Mol Cell. 2018;69:87-99.e7 pubmed publisher
Qian X, Li X, Tan L, Lee J, Xia Y, Cai Q, et al. Conversion of PRPS Hexamer to Monomer by AMPK-Mediated Phosphorylation Inhibits Nucleotide Synthesis in Response to Energy Stress. Cancer Discov. 2018;8:94-107 pubmed publisher
Mahapatra G, Varughese A, Ji Q, Lee I, Liu J, Vaishnav A, et al. Phosphorylation of Cytochrome c Threonine 28 Regulates Electron Transport Chain Activity in Kidney: IMPLICATIONS FOR AMP KINASE. J Biol Chem. 2017;292:64-79 pubmed publisher
Treebak J, Taylor E, Witczak C, An D, Toyoda T, Koh H, et al. Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. Am J Physiol Cell Physiol. 2010;298:C377-85 pubmed publisher
Taylor E, An D, Kramer H, Yu H, Fujii N, Roeckl K, et al. Discovery of TBC1D1 as an insulin-, AICAR-, and contraction-stimulated signaling nexus in mouse skeletal muscle. J Biol Chem. 2008;283:9787-96 pubmed publisher

product information

Catalog Number :

P47-10H

Product Name :

AMPK (A1/B1/G1), Active

Product Type :

Protein

Host Species :

Baculovirus-Insect Cells

Conjugation :

C-His

Size :

10 µg

List Price :

658 USD

Gene ID :

NM_006251 ,NM_006253 ,NM_002733

Product Description :

Recombinant full length human AMPK (combination of A1/B1/G1 subunits) was expressed by baculovirus in Sf9 insect cells using C-terminal His tags.

SpeciesSummary :

Human

ALTnames :

PRKAG1 & PRKAB1 & PRKAA1

Purity :

For specific information on a given lot, see related technical data sheet.

Buffer :

Supplied as sterile 50 mM sodium phosphate, pH 7.5, 300mM NaCl, 50-200mM imidazole, 0-0.1mM PMSF, 0.2-1.0mM DTT, 10-25% glycerol

Packaging :

Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.

Storage :

Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

more info or order :

Sino Biological product webpage