product summary
Loading...
company name :
Sino Biological
product type :
protein
product name :
HDAC4, Active
catalog :
H86-31G
quantity :
10 µg
price :
158 USD
more info or order :
Sino Biological product webpage
citations: 5
Reference
Jiang X, Tu F, Wei L, Wang B, Yuan H, Yuan J, et al. Discovery of a Novel G-Quadruplex and Histone Deacetylase (HDAC) Dual-Targeting Agent for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2022;65:12346-12366 pubmed publisher
Huang Y, Dong G, Li H, Liu N, Zhang W, Sheng C. Discovery of Janus Kinase 2 (JAK2) and Histone Deacetylase (HDAC) Dual Inhibitors as a Novel Strategy for the Combinational Treatment of Leukemia and Invasive Fungal Infections. J Med Chem. 2018;61:6056-6074 pubmed publisher
Dong G, Chen W, Wang X, Yang X, Xu T, Wang P, et al. Small Molecule Inhibitors Simultaneously Targeting Cancer Metabolism and Epigenetics: Discovery of Novel Nicotinamide Phosphoribosyltransferase (NAMPT) and Histone Deacetylase (HDAC) Dual Inhibitors. J Med Chem. 2017;60:7965-7983 pubmed publisher
Duan W, Li J, Inks E, Chou C, Jia Y, Chu X, et al. Design, synthesis, and antitumor evaluation of novel histone deacetylase inhibitors equipped with a phenylsulfonylfuroxan module as a nitric oxide donor. J Med Chem. 2015;58:4325-38 pubmed publisher
Hou X, Du J, Liu R, Zhou Y, Li M, Xu W, et al. Enhancing the Sensitivity of Pharmacophore-Based Virtual Screening by Incorporating Customized ZBG Features: A Case Study Using Histone Deacetylase 8. J Chem Inf Model. 2015;55:861-71 pubmed publisher
product information
Catalog Number :
H86-31G
Product Name :
HDAC4, Active
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
N-GST
Size :
10 µg
List Price :
158 USD
Gene ID :
NM_006037
Product Description :
Recombinant human HDAC4 (612-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
SpeciesSummary :
Human
ALTnames :
AHO3,BDMR,HA6116,HD4,HDAC-4,HDACA,HDAC-A,NEDCHF,NEDCHID,KIAA0288,HDAC4
Purity :
For specific information on a given lot, see related technical data sheet.
Buffer :
Supplied as sterile 50 mM Tris-HCl, pH 7.5, 50-300mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25-1.0mM DTT, 0-0.1mM PMSF, 10-25% glycerol
Packaging :
Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage :
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.