product summary
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company name :
Sino Biological
product type :
protein
product name :
Human CDK7 & CCNH & MNAT1 Heterotrimer Protein
catalog :
CT020-H07B
quantity :
50 µg
price :
258 USD
more info or order :
Sino Biological product webpage
citations: 4
Reference
Zhang H, Lin G, Jia S, Wu J, Zhang Y, Tao Y, et al. Design, synthesis and evaluation of thieno[3,2-d]pyrimidine derivatives as novel potent CDK7 inhibitors. Bioorg Chem. 2024;148:107456 pubmed publisher
Niu P, Tao Y, Lin G, Xu H, Meng Q, Yang K, et al. Design and Synthesis of Novel Macrocyclic Derivatives as Potent and Selective Cyclin-Dependent Kinase 7 Inhibitors. J Med Chem. 2024;67:6099-6118 pubmed publisher
Niu P, Tao Y, Meng Q, Huang Y, Li S, Ding K, et al. Discovery of novel macrocyclic derivatives as potent and selective cyclin-dependent kinase 2 inhibitors. Bioorg Med Chem. 2024;104:117711 pubmed publisher
Zhang H, Lin G, Jia S, Zhang Y, Wu J, Tao Y, et al. Discovery and optimization of thieno[3,2-d]pyrimidine derivatives as highly selective inhibitors of cyclin-dependent kinase 7. Eur J Med Chem. 2024;263:115955 pubmed publisher
image
image 1 :
Sino Biological CT020-H07B image 1
product information
Catalog Number :
CT020-H07B
Product Name :
Human CDK7 & CCNH & MNAT1 Heterotrimer Protein
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
N-His
Size :
50 µg
List Price :
258 USD
Gene ID :
P50613 & P51946 & P51948
Product Description :
A DNA sequence encoding the human CDK7 (P50613) (Ala 2-Phe 346) was fused with a polyhistidine tag at the N-terminus, constructed the plasmid 1; A DNA sequence encoding the human CCNH (P51946) (Tyr 2-Leu 323) was fused with a polyhistidine tag at the N-terminus, constructed the plasmid 2. A DNA sequence encoding the human MNAT1 (P51948) (Asp 2-Ser 309) was fused with a polyhistidine tag at the N-terminus, constructed the plasmid 3. The three plasmids were co-expressed and the heterotrimer was purified.
SpeciesSummary :
Human
ALTnames :
CDK7 & CCNH & MNAT1
Purity :
> 85 % as determined by SDS-PAGE
Buffer :
Supplied as sterile 20 mM Tris, 500 mM NaCl, 10% glycerol, pH 7.5.
Packaging :
Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.