product summary
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company name :
Sino Biological
product type :
protein
product name :
Human FCGRT & B2M Heterodimer Protein (His Tag)
catalog :
CT009-H08H
quantity :
1 mg
price :
2248 USD
more info or order :
Sino Biological product webpage
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human
Latvala S, Jacobsen B, Otteneder M, Herrmann A, Kronenberg S. Distribution of FcRn Across Species and Tissues. J Histochem Cytochem. 2017;65:321-333 pubmed publisher
Kim D, Kim S, Byeon J, Lee H, Kim J, Kim H, et al. Engineering IgG antibodies for intracellular targeting and drug delivery. J Control Release. 2025;382:113727 pubmed publisher
Lv Y, Chen J, Wang C, Jin Z, Lou J. An antibody against human interleukin-2 showing minimal binding to neonatal Fc receptor: Potent anti-tumor activity and reduced systemic toxicity in mice. Eur J Pharmacol. 2025;987:177159 pubmed publisher
Zhou C, Jiang J, Xiang X, Liu H, Wu G, Zeng R, et al. Preclinical investigations and a first-in-human phase 1a trial of JS007, a novel anti-CTLA-4 antibody, in patients with advanced solid tumors. Exp Hematol Oncol. 2024;13:98 pubmed publisher
Zhou F, Ben Y, Jiang H, Tan S, Mu G, Zha Z, et al. A Novel Dual-Fc Bispecific Antibody with Enhanced Fc Effector Function. Biochemistry. 2024;63:958-968 pubmed publisher
Park J, Choi H, Jung K, Lee K, Shim J, Park K, et al. Production of recombinant human IgG1 Fc with beneficial N-glycosylation pattern for anti-inflammatory activity using genome-edited chickens. Commun Biol. 2023;6:589 pubmed publisher
Yadav P, Mendiratta S, Mohandas S, Singh A, Abraham P, Shete A, et al. ZRC3308 Monoclonal Antibody Cocktail Shows Protective Efficacy in Syrian Hamsters against SARS-CoV-2 Infection. Viruses. 2021;13: pubmed publisher
Noy Porat T, Edri A, Alcalay R, Makdasi E, Gur D, Aftalion M, et al. Fc-Independent Protection from SARS-CoV-2 Infection by Recombinant Human Monoclonal Antibodies. Antibodies (Basel). 2021;10: pubmed publisher
Rosenfeld R, Noy Porat T, Mechaly A, Makdasi E, Levy Y, Alcalay R, et al. Post-exposure protection of SARS-CoV-2 lethal infected K18-hACE2 transgenic mice by neutralizing human monoclonal antibody. Nat Commun. 2021;12:944 pubmed publisher
Wada R, Matsui M, Kawasaki N. Influence of N-glycosylation on effector functions and thermal stability of glycoengineered IgG1 monoclonal antibody with homogeneous glycoforms. MAbs. 2019;11:350-372 pubmed publisher
Goulet D, Watson M, Tam S, Zwolak A, Chiu M, Atkins W, et al. Toward a Combinatorial Approach for the Prediction of IgG Half-Life and Clearance. Drug Metab Dispos. 2018;46:1900-1907 pubmed publisher
image
image 1 :
Sino Biological CT009-H08H image 1
product information
Catalog Number :
CT009-H08H
Product Name :
Human FCGRT & B2M Heterodimer Protein (His Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-His
Size :
1 mg
List Price :
2248 USD
Gene ID :
P55899-1 & P61769
Product Description :
A DNA sequence encoding the extracellular domain (Met1-Ser297) of human FCGRT (P55899-1) was fused with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human B2M (P61769) (Met1-Met119) constructed the plasmid 2. The two plasmids were co-expressed and the FCGRT / B2M heterodimer was purified.
SpeciesSummary :
Human
ALTnames :
FCGRT & B2M
Purity :
≥ 95 % as determined by SDS-PAGE, ≥ 90 % as determined by SEC-HPLC, ≥ 90% as determined by SEC-MALS(Routinely tested).
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.