product summary
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company name :
Sino Biological
product type :
protein
product name :
AKT1, Active
catalog :
A16-10G
quantity :
10 µg
price :
278 USD
more info or order :
Sino Biological product webpage
citations: 15
Reference
Blawski R, Vokshi B, Guo X, Kittane S, Sallaku M, Chen W, et al. Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer. Cell Rep. 2024;43:114174 pubmed publisher
Wu K, Yan M, Liu T, Wang Z, Duan Y, Xia Y, et al. Creatine kinase B suppresses ferroptosis by phosphorylating GPX4 through a moonlighting function. Nat Cell Biol. 2023;25:714-725 pubmed publisher
Wu S, Cao R, Tao B, Wu P, Peng C, Gao H, et al. Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma. Adv Sci (Weinh). 2022;9:e2104055 pubmed publisher
Zhu L, Chen X, Zhu Y, Qin J, Niu T, Ding Y, et al. Dihydroartemisinin Inhibits the Proliferation of Esophageal Squamous Cell Carcinoma Partially by Targeting AKT1 and p70S6K. Front Pharmacol. 2020;11:587470 pubmed publisher
Kalpage H, Wan J, Morse P, Lee I, Huttemann M. Brain-Specific Serine-47 Modification of Cytochrome c Regulates Cytochrome c Oxidase Activity Attenuating ROS Production and Cell Death: Implications for Ischemia/Reperfusion Injury and Akt Signaling. Cells. 2020;9: pubmed publisher
Kim J, Lee D, Kim T, Park H, Kim M, Kang T. PLPP/CIN-mediated Mdm2 dephosphorylation increases seizure susceptibility via abrogating PSD95 ubiquitination. Exp Neurol. 2020;331:113383 pubmed publisher
Xu D, Wang Z, Xia Y, Shao F, Xia W, Wei Y, et al. The gluconeogenic enzyme PCK1 phosphorylates INSIG1/2 for lipogenesis. Nature. 2020;580:530-535 pubmed publisher
Toska E, Castel P, Chhangawala S, Arruabarrena Aristorena A, Chan C, Hristidis V, et al. PI3K Inhibition Activates SGK1 via a Feedback Loop to Promote Chromatin-Based Regulation of ER-Dependent Gene Expression. Cell Rep. 2019;27:294-306.e5 pubmed publisher
Lee J, Liu R, Li J, Zhang C, Wang Y, Cai Q, et al. Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis. Nat Commun. 2017;8:949 pubmed publisher
Gu Y, Albuquerque C, Braas D, Zhang W, Villa G, Bi J, et al. mTORC2 Regulates Amino Acid Metabolism in Cancer by Phosphorylation of the Cystine-Glutamate Antiporter xCT. Mol Cell. 2017;67:128-138.e7 pubmed publisher
Waldhart A, Dykstra H, Peck A, Boguslawski E, Madaj Z, Wen J, et al. Phosphorylation of TXNIP by AKT Mediates Acute Influx of Glucose in Response to Insulin. Cell Rep. 2017;19:2005-2013 pubmed publisher
Zhang Y, Stefanovic B. Akt mediated phosphorylation of LARP6; critical step in biosynthesis of type I collagen. Sci Rep. 2016;6:22597 pubmed publisher
Dastidar S, Landrieu P, D Mello S. FoxG1 promotes the survival of postmitotic neurons. J Neurosci. 2011;31:402-13 pubmed publisher
Treebak J, Taylor E, Witczak C, An D, Toyoda T, Koh H, et al. Identification of a novel phosphorylation site on TBC1D4 regulated by AMP-activated protein kinase in skeletal muscle. Am J Physiol Cell Physiol. 2010;298:C377-85 pubmed publisher
Pecorari L, Marin O, Silvestri C, Candini O, Rossi E, Guerzoni C, et al. Elongation Factor 1 alpha interacts with phospho-Akt in breast cancer cells and regulates their proliferation, survival and motility. Mol Cancer. 2009;8:58 pubmed publisher
product information
Catalog Number :
A16-10G
Product Name :
AKT1, Active
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
N-GST
Size :
10 µg
List Price :
278 USD
Gene ID :
NM_005163
Product Description :
Recombinant full length human AKT1 was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
SpeciesSummary :
Human
ALTnames :
AKT,PKB,PKB-ALPHA,PRKBA,RAC,RAC-ALPHA,AKT1
Purity :
For specific information on a given lot, see related technical data sheet.
Buffer :
Supplied as sterile 50 mM Tris-HCl, pH 7.5, 50-300mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25-1.0mM DTT, 0-0.1mM PMSF, 10-25% glycerol
Packaging :
Enzymes are highly recommended to be shipped at frozen temperature with dry ice. Shipment made at ambient temperature may seriously affect the activity of the ordered products.
Storage :
Store product at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.