product summary
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company name :
Sino Biological
product type :
protein
product name :
Mouse TNF-alpha / TNFA Protein (ECD)
catalog :
50349-MNAE
quantity :
1 mg
price :
2268 USD
more info or order :
Sino Biological product webpage
citations: 15
Reference
Tao X, Chen H, Zhu Z, Ren T, Zhen H, Sun X, et al. Astrocyte-conditional knockout of MOB2 inhibits the phenotypic conversion of reactive astrocytes from A1 to A2 following spinal cord injury in mice. Int J Biol Macromol. 2025;300:140289 pubmed publisher
Zhang N, Liu J, Guo R, Yan L, Yang Y, Shi C, et al. Palmitoylation licenses RIPK1 kinase activity and cytotoxicity in the TNF pathway. Mol Cell. 2024;84:4419-4435.e10 pubmed publisher
Qiu J, Wang Y, Wang X, Chen H. PI3Kδ inhibition alleviates the brain injury during cerebral ischemia reperfusion via suppressing pericyte contraction in a TNF-α dependent manner. Exp Neurol. 2024;375:114728 pubmed publisher
Ge D, Chen Q, Xie X, Li Q, Yang Y. Unveiling the potent effect of vitamin D: harnessing Nrf2/HO-1 signaling pathways as molecular targets to alleviate urban particulate matter-induced asthma inflammation. BMC Pulm Med. 2024;24:55 pubmed publisher
Hou S, Zhang J, Jiang X, Yang Y, Shan B, Zhang M, et al. PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis. Mol Cell. 2024;84:938-954.e8 pubmed publisher
Yan T, Wang R, Yao J, Luo M. Single-cell transcriptomic analysis reveals rich pituitary-Immune interactions under systemic inflammation. PLoS Biol. 2023;21:e3002403 pubmed publisher
Lin J, Lan Y, Xiang D, Ma R, Chen Q, Ding K, et al. IL-33 promotes pancreatic β-cell survival and insulin secretion under diabetogenic conditions through PPARγ. Eur J Pharmacol. 2023;959:176059 pubmed publisher
Li M, Wei J, Zhu G, Fu S, He X, Hu X, et al. Quizartinib inhibits necroptosis by targeting receptor-interacting serine/threonine protein kinase 1. FASEB J. 2023;37:e23178 pubmed publisher
He X, Li M, Ye Z, You X, Wang J, Xiao X, et al. Identification of Piperlongumine as Potent Inhibitor of Necroptosis. Drug Des Devel Ther. 2023;17:1387-1394 pubmed publisher
Yu L, Yang K, He X, Li M, Gao L, Zha Y. Repositioning linifanib as a potent anti-necroptosis agent for sepsis. Cell Death Discov. 2023;9:57 pubmed publisher
Yu Y, Li M, Fu S, He X, Hu X, Zhu G, et al. Repurposing crizotinib to target RIPK1-dependent cell death. Int Immunol. 2023;35:221-230 pubmed publisher
Ji K, Wu M, Huang C, GongPan P, Sun P, Sun Y, et al. Alpinia hainanensis Rhizome Extract Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis: Active Ingredient Investigation and Evaluation. J Agric Food Chem. 2022;70:3989-3999 pubmed publisher
Gao G, Zhao S, Xia X, Li C, Li C, Ji C, et al. Glutaminase C Regulates Microglial Activation and Pro-inflammatory Exosome Release: Relevance to the Pathogenesis of Alzheimer's Disease. Front Cell Neurosci. 2019;13:264 pubmed publisher
Jeschke A, Catala Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, et al. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells. J Immunol. 2015;195:3675-84 pubmed publisher
Sieber S, Lange N, Kollmorgen G, Erhardt A, Quaas A, Gontarewicz A, et al. Sharpin contributes to TNF? dependent NF?B activation and anti-apoptotic signalling in hepatocytes. PLoS ONE. 2012;7:e29993 pubmed publisher
image
image 1 :
Sino Biological 50349-MNAE image 1
product information
Catalog Number :
50349-MNAE
Product Name :
Mouse TNF-alpha / TNFA Protein (ECD)
Product Type :
Protein
Host Species :
E. coli
Conjugation :
Native
Size :
1 mg
List Price :
2268 USD
Gene ID :
NP_038721.1
Product Description :
A DNA sequence encoding the soluble form of mouse TNF-α (NP_038721.1) (Leu 80-Leu 235) was expressed, with an initial Met at the N-terminus.
SpeciesSummary :
Mouse
ALTnames :
DIF,Tnfa,TNF-a,TNFalpha,TNF-alpha,Tnfsf1a,TNFSF2,Tnlg1f,Tnf
Purity :
≥ 95 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH7.4
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.