product summary
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company name :
Sino Biological
product type :
protein
product name :
Mouse CD32 / FCGR2B Protein (His & AVI Tag), Biotinylated
catalog :
50030-M27H-B
quantity :
100 µg
price :
688 USD
more info or order :
citations: 6
Reference
Slein M, Backes I, Garland C, Kelkar N, Leib D, Ackerman M. Effector functions are required for broad and potent protection of neonatal mice with antibodies targeting HSV glycoprotein D. Cell Rep Med. 2024;5:101417 pubmed publisher
Sahin M, Remy M, Fallet B, Sommerstein R, Florova M, Langner A, et al. Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors. Cell Rep. 2022;38:110303 pubmed publisher
Zeeuw van der Laan E, van der Velden S, Bentlage A, Larsen M, van Osch T, Mok J, et al. Biological and structural characterization of murine TRALI antibody reveals increased Fc-mediated complement activation. Blood Adv. 2020;4:3875-3885 pubmed publisher
Sow H, Benonisson H, Breukel C, Visser R, Verhagen O, Bentlage A, et al. FcγR interaction is not required for effective anti-PD-L1 immunotherapy but can add additional benefit depending on the tumor model. Int J Cancer. 2019;144:345-354 pubmed publisher
Dekkers G, Bentlage A, Plomp R, Visser R, Koeleman C, Beentjes A, et al. Conserved FcγR- glycan discriminates between fucosylated and afucosylated IgG in humans and mice. Mol Immunol. 2018;94:54-60 pubmed publisher
Dekkers G, Bentlage A, Stegmann T, Howie H, Lissenberg Thunnissen S, ZIMRING J, et al. Affinity of human IgG subclasses to mouse Fc gamma receptors. MAbs. 2017;9:767-773 pubmed publisher
image
image 1 :
Sino Biological 50030-M27H-B image 1
product information
Catalog Number :
50030-M27H-B
Product Name :
Mouse CD32 / FCGR2B Protein (His & AVI Tag), Biotinylated
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-AVI & His
Size :
100 µg
List Price :
688 USD
Gene ID :
NP_001070657.1
Product Description :
A DNA sequence encoding the extracellular domain (Met 1-Arg 217) of mouse FGGR2B (NP_001070657.1) as fused with a c-terminal polyhistidine tagged AVI tag at the C-terminus. The expressed protein was biotinylated in vivo by the Biotin-Protein ligase (BirA enzyme) which is co-expressed.
SpeciesSummary :
Mouse
ALTnames :
CD32,F630109E10Rik,Fc[g]RII,Fcgr2,FcgRII,Fcr-2,Fcr-3,fcRII,Ly-17,LyM-1,Ly-m20
Purity :
> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.