Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His Tag) | Sino Biological 50010-M08H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His Tag)

catalog :

50010-M08H

quantity :

1 mg

price :

1618 USD

more info or order :

Sino Biological product webpage

citations: 17

Published Application/Species/Sample/Dilution	Reference
ELISA; mouse	Broos K, Keyaerts M, Lecocq Q, Renmans D, Nguyen T, Escors D, et al. Non-invasive assessment of murine PD-L1 levels in syngeneic tumor models by nuclear imaging with nanobody tracers. Oncotarget. 2017;8:41932-41946 pubmed publisher
	Okpalanwaka I, Daugherity E, McCormick A, Anderson T, Smith S, Lawrence C, et al. A PD-L1/CD3 Bispecific Antibody Enhances the Antitumor Effects of Regorafenib against Colon Cancer. Mol Cancer Ther. 2025;24:1240-1251 pubmed publisher
	Wang S, Kong Z, Shi Y, Shao C, Wang W, Su Z, et al. Discovery of Small and Bifunctional Molecules Targeting PD-L1/CD73 for Cancer Dual Immunotherapy. J Med Chem. 2024;67:9447-9464 pubmed publisher
	Xu Y, Du H, Guo W, Liu B, Yan W, Zhang C, et al. Discovery of Highly Potent Small-Molecule PD-1/PD-L1 Inhibitors with a Novel Scaffold for Cancer Immunotherapy. J Med Chem. 2024;67:4083-4099 pubmed publisher
	Cohen Saban N, Yalin A, Landsberger T, Salomon R, Alva A, Feferman T, et al. Fc glycoengineering of a PD-L1 antibody harnesses Fcγ receptors for increased antitumor efficacy. Sci Immunol. 2023;8:eadd8005 pubmed publisher
	Liu W, So W, Harden S, Fong S, Wong M, Tan W, et al. Successful targeting of PD-1/PD-L1 with chimeric antigen receptor-natural killer cells and nivolumab in a humanized mouse cancer model. Sci Adv. 2022;8:eadd1187 pubmed publisher
	Jiao L, Dong Q, Zhai W, Zhao W, Shi P, Wu Y, et al. A PD-L1 and VEGFR2 dual targeted peptide and its combination with irradiation for cancer immunotherapy. Pharmacol Res. 2022;182:106343 pubmed publisher
	Cao H, Cheng B, Liu T, Chen J. Synthesis and pharmacological evaluation of novel resorcinol biphenyl ether analogs as small molecule inhibitors of PD-1/PD-L1 with benign toxicity profiles for cancer treatment. Biochem Pharmacol. 2021;188:114522 pubmed publisher
	Cheng B, Wang W, Niu X, Ren Y, Liu T, Cao H, et al. Discovery of Novel and Highly Potent Resorcinol Dibenzyl Ether-Based PD-1/PD-L1 Inhibitors with Improved Drug-like and Pharmacokinetic Properties for Cancer Treatment. J Med Chem. 2020;63:15946-15959 pubmed publisher
	Gao H, Wu Y, Shi J, Zhang X, Liu T, Hu B, et al. Nuclear imaging-guided PD-L1 blockade therapy increases effectiveness of cancer immunotherapy. J Immunother Cancer. 2020;8: pubmed publisher
	Xu J, Wang J, Wang X, Tan R, Qi X, Liu Z, et al. Soluble PD-L1 improved direct ARDS by reducing monocyte-derived macrophages. Cell Death Dis. 2020;11:934 pubmed publisher
	Xu X, Hou B, Fulzele A, Masubuchi T, Zhao Y, Wu Z, et al. PD-1 and BTLA regulate T cell signaling differentially and only partially through SHP1 and SHP2. J Cell Biol. 2020;219: pubmed publisher
	Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
	Li C, Course M, McNeish I, Drescher C, Valdmanis P, Lieber A. Prophylactic In Vivo Hematopoietic Stem Cell Gene Therapy with an Immune Checkpoint Inhibitor Reverses Tumor Growth in Syngeneic Mouse Tumor Models. Cancer Res. 2020;80:549-560 pubmed publisher
	Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed publisher
	Li C, Zhang N, Zhou J, Ding C, Jin Y, Cui X, et al. Peptide Blocking of PD-1/PD-L1 Interaction for Cancer Immunotherapy. Cancer Immunol Res. 2018;6:178-188 pubmed publisher
	Drees J, Augustin L, Mertensotto M, Schottel J, Leonard A, Saltzman D. Soluble production of a biologically active single-chain antibody against murine PD-L1 in Escherichia coli. Protein Expr Purif. 2014;94:60-6 pubmed publisher

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product information

Catalog Number :

50010-M08H

Product Name :

Mouse PD-L1 / B7-H1 / CD274 Protein (ECD,His Tag)

Product Type :

Protein

Host Species :

HEK293 Cells

Conjugation :

C-His

Size :

1 mg

List Price :

1618 USD

Gene ID :

NP_068693.1

Product Description :

A DNA sequence encoding the mouse CD274 (NP_068693.1) extracellular domain (Met 1-Thr 238) was fused with a polyhistidine tag at the C-terminus.

SpeciesSummary :

Mouse

ALTnames :

A530045L16Rik,B7h1,Pdcd1l1,Pdcd1lg1,Pdl1,Cd274

Purity :

> 98 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage