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company name :
Sino Biological
product type :
protein
product name :
SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)
catalog :
40634-V08B
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 16
Reference
Meany E, Klich J, Jons C, Mao T, Chaudhary N, Utz A, et al. Generation of an inflammatory niche in a hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines. Sci Adv. 2025;11:eadr2631 pubmed publisher
Meany E, Klich J, Jons C, Mao T, Chaudhary N, Utz A, et al. Generation of an inflammatory niche in an injectable hydrogel depot through recruitment of key immune cells improves efficacy of mRNA vaccines. bioRxiv. 2024;: pubmed publisher
Heo C, Lim W, Yang J, Son S, Kim S, Kim D, et al. Novel S2 subunit-specific antibody with broad neutralizing activity against SARS-CoV-2 variants of concern. Front Immunol. 2023;14:1307693 pubmed publisher
Peng L, Fang Z, Renauer P, McNamara A, Park J, Lin Q, et al. Multiplexed LNP-mRNA vaccination against pathogenic coronavirus species. Cell Rep. 2022;40:111160 pubmed publisher
Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol. 2022;7:1063-1074 pubmed publisher
Chen Y, Tong P, WHITEMAN N, Moghaddam A, Zarghami M, Zuiani A, et al. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants. Sci Immunol. 2022;:eabp8328 pubmed publisher
Lai G, Chao T, Lin S, Kao H, Tsai Y, Lu D, et al. Neutralization or enhancement of SARS-CoV-2 infection by a monoclonal antibody targeting a specific epitope in the spike receptor-binding domain. Antiviral Res. 2022;200:105290 pubmed publisher
Li C, Chao T, Chang T, Hsiao C, Lu D, Chiang Y, et al. Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion. Microbiol Spectr. 2022;10:e0181421 pubmed publisher
Li M, Liu J, Lu R, Zhang Y, Du M, Xing M, et al. Longitudinal immune profiling reveals dominant epitopes mediating long-term humoral immunity in COVID-19-convalescent individuals. J Allergy Clin Immunol. 2022;149:1225-1241 pubmed publisher
Boonyaratanakornkit J, Sholukh A, Gray M, Bossard E, Ford E, Corbett K, et al. Methods to Measure Antibody Neutralization of Live Human Coronavirus OC43. Viruses. 2021;13: pubmed publisher
Low J, Vaqueirinho D, Mele F, Foglierini M, Jerak J, Perotti M, et al. Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2. Science. 2021;372:1336-1341 pubmed publisher
Bojadzic D, Alcazar O, Chen J, Chuang S, Condor Capcha J, Shehadeh L, et al. Small-Molecule Inhibitors of the Coronavirus Spike: ACE2 Protein-Protein Interaction as Blockers of Viral Attachment and Entry for SARS-CoV-2. ACS Infect Dis. 2021;7:1519-1534 pubmed publisher
Zhao M, Yang W, Yang F, Zhang L, Huang W, Hou W, et al. Cathepsin L plays a key role in SARS-CoV-2 infection in humans and humanized mice and is a promising target for new drug development. Signal Transduct Target Ther. 2021;6:134 pubmed publisher
Ren W, Zhu Y, Wang Y, Shi H, Yu Y, Hu G, et al. Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry. PLoS Pathog. 2021;17:e1009392 pubmed publisher
Bojadzic D, Alcazar O, Buchwald P. Methylene Blue Inhibits the SARS-CoV-2 Spike-ACE2 Protein-Protein Interaction-a Mechanism that can Contribute to its Antiviral Activity Against COVID-19. Front Pharmacol. 2020;11:600372 pubmed publisher
Kim S, Jin W, Sood A, Montgomery D, Grant O, Fuster M, et al. Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions. Antiviral Res. 2020;:104873 pubmed publisher
image
image 1 :
Sino Biological 40634-V08B image 1
product information
Catalog Number :
40634-V08B
Product Name :
SARS-CoV Spike S1+S2 ECD-His Recombinant Protein (S577A, Isolate Tor2)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
NP_828851.1
Product Description :
A DNA sequence encoding the full-lenght ECD of SARS-CoV (isolate: Tor2) spike (NP_828851.1) (Met1-Pro1195) was expressed with a C-terminal polyhistidine tag.
SpeciesSummary :
SARS
ALTnames :
Spike
Purity :
> 90 % as determined by SDS-PAGE.
Buffer :
Lyophilized from sterile 20mM PB, 300mM NaCl, pH 7.0, 10% glycerol
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.