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company name :
Sino Biological
product type :
protein
product name :
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His Tag)
catalog :
40606-V08B
quantity :
100 µg
price :
448 USD
more info or order :
citations: 20
Reference
Cheng X, Shen H, Zhang W, Chen B, Xu S, Wu L. Characterizing the effects of triclosan and triclocarban on the intestinal epithelial homeostasis using small intestinal organoids. J Hazard Mater. 2024;479:135734 pubmed publisher
Li Z, Obraztsova A, Shang F, Oludada O, Malapit J, Busch K, et al. Affinity-independent memory B cell origin of the early antibody-secreting cell response in naive individuals upon SARS-CoV-2 vaccination. Immunity. 2024;57:2191-2201.e5 pubmed publisher
Heo C, Lim W, Yang J, Son S, Kim S, Kim D, et al. Novel S2 subunit-specific antibody with broad neutralizing activity against SARS-CoV-2 variants of concern. Front Immunol. 2023;14:1307693 pubmed publisher
Anderson E, Li S, Awofolaju M, Eilola T, Goodwin E, Bolton M, et al. SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. Cell Rep. 2022;41:111496 pubmed publisher
Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol. 2022;7:1063-1074 pubmed publisher
Chen Y, Tong P, WHITEMAN N, Moghaddam A, Zarghami M, Zuiani A, et al. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants. Sci Immunol. 2022;:eabp8328 pubmed publisher
Dacon C, Tucker C, Peng L, Lee C, Lin T, Yuan M, et al. Broadly neutralizing antibodies target the coronavirus fusion peptide. bioRxiv. 2022;: pubmed publisher
Lanz T, Brewer R, Jahanbani S, Robinson W. Limited Neutralization of Omicron by Antibodies from the BNT162b2 Vaccination against SARS-CoV-2. Res Sq. 2022;: pubmed publisher
Minervina A, Pogorelyy M, Kirk A, Crawford J, Allen E, Chou C, et al. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells. Nat Immunol. 2022;23:781-790 pubmed publisher
Pattinson D, Jester P, Guan L, Yamayoshi S, Chiba S, Presler R, et al. A Novel Method to Reduce ELISA Serial Dilution Assay Workload Applied to SARS-CoV-2 and Seasonal HCoVs. Viruses. 2022;14: pubmed publisher
Narowski T, Raphel K, Adams L, Huang J, Vielot N, Jadi R, et al. SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people. Cell Rep. 2022;38:110336 pubmed publisher
Lin C, Wolf J, Brice D, Sun Y, Locke M, Cherry S, et al. Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response. Cell Host Microbe. 2022;30:83-96.e4 pubmed publisher
Lapp S, Edara V, Lu A, Lai L, Hussaini L, Chahroudi A, et al. Original antigenic sin responses to Betacoronavirus spike proteins are observed in a mouse model, but are not apparent in children following SARS-CoV-2 infection. PLoS ONE. 2021;16:e0256482 pubmed publisher
Minervina A, Pogorelyy M, Kirk A, Allen E, Allison K, Lin C, et al. Convergent epitope-specific T cell responses after SARS-CoV-2 infection and vaccination. medRxiv. 2021;: pubmed publisher
Jennewein M, MacCamy A, Akins N, Feng J, Homad L, Hurlburt N, et al. Isolation and characterization of cross-neutralizing coronavirus antibodies from COVID-19+ subjects. Cell Rep. 2021;36:109353 pubmed publisher
Low J, Vaqueirinho D, Mele F, Foglierini M, Jerak J, Perotti M, et al. Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2. Science. 2021;372:1336-1341 pubmed publisher
Klausberger M, Duerkop M, Haslacher H, Wozniak Knopp G, Cserjan Puschmann M, Perkmann T, et al. A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests. EBioMedicine. 2021;67:103348 pubmed publisher
Cho H, Gonzales Wartz K, Huang D, Yuan M, Peterson M, Liang J, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. bioRxiv. 2021;: pubmed publisher
Sakharkar M, Rappazzo C, Wieland Alter W, Hsieh C, Wrapp D, Esterman E, et al. Prolonged evolution of the human B cell response to SARS-CoV-2 infection. Sci Immunol. 2021;6: pubmed publisher
Zhu B, Tang L, Chen S, Yin C, Peng S, Li X, et al. Targeting the upstream transcriptional activator of PD-L1 as an alternative strategy in melanoma therapy. Oncogene. 2018;37:4941-4954 pubmed publisher
image
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Sino Biological 40606-V08B image 1
product information
Catalog Number :
40606-V08B
Product Name :
Human coronavirus HKU1 (isolate N5) (HCoV-HKU1) Spike Protein (S1+S2 ECD, His Tag)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
Q0ZME7.1
Product Description :
A DNA sequence encoding the human coronavirus HKU1 (isolate N5) (HCoV-HKU1) spike protein (S1+S2 ECD) (Q0ZME7.1) (Met1-Pro1295) was expressed with a polyhistidine tag at the C-terminus.
SpeciesSummary :
HCoV-HKU1
ALTnames :
Spike
Purity :
> 75 % as determined by SDS-PAGE.
Buffer :
Lyophilized from sterile 20 mM PB, 300 mM NaCl, 10 % glycerol, pH 7.5
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.