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company name :
Sino Biological
product type :
protein
product name :
Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His Tag)
catalog :
40605-V08B
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 16
Reference
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Li S, Ye F, Zheng Y, Wang J, Peng H, Zhu L, et al. Dual-Locking the SARS-CoV-2 Spike Trimer: An Amphipathic Molecular "Bolt" Stabilizes Conserved Druggable Interfaces for Coronavirus Inhibition. Adv Sci (Weinh). 2025;12:e2417534 pubmed publisher
Tasi x107 N, Konjevi x107 I, Lobato A, Metarapi D, Fin x161 gar M, Oliveira F, et al. Study of V2CTx-MXene Based Immunosensor for Sensitive Label-Free Impedimetric Detection of SARS-CoV-2 Spike Protein. ACS Appl Mater Interfaces. 2024;16:30196-30208 pubmed publisher
Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol. 2022;7:1063-1074 pubmed publisher
Chen Y, Tong P, WHITEMAN N, Moghaddam A, Zarghami M, Zuiani A, et al. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants. Sci Immunol. 2022;:eabp8328 pubmed publisher
Dacon C, Tucker C, Peng L, Lee C, Lin T, Yuan M, et al. Broadly neutralizing antibodies target the coronavirus fusion peptide. bioRxiv. 2022;: pubmed publisher
Minervina A, Pogorelyy M, Kirk A, Crawford J, Allen E, Chou C, et al. SARS-CoV-2 antigen exposure history shapes phenotypes and specificity of memory CD8+ T cells. Nat Immunol. 2022;23:781-790 pubmed publisher
Narowski T, Raphel K, Adams L, Huang J, Vielot N, Jadi R, et al. SARS-CoV-2 mRNA vaccine induces robust specific and cross-reactive IgG and unequal neutralizing antibodies in naive and previously infected people. Cell Rep. 2022;38:110336 pubmed publisher
Lin C, Wolf J, Brice D, Sun Y, Locke M, Cherry S, et al. Pre-existing humoral immunity to human common cold coronaviruses negatively impacts the protective SARS-CoV-2 antibody response. Cell Host Microbe. 2022;30:83-96.e4 pubmed publisher
Boonyaratanakornkit J, Sholukh A, Gray M, Bossard E, Ford E, Corbett K, et al. Methods to Measure Antibody Neutralization of Live Human Coronavirus OC43. Viruses. 2021;13: pubmed publisher
Chan M, Vijay S, McNevin J, McElrath M, Holland E, Gujral T. Machine learning identifies molecular regulators and therapeutics for targeting SARS-CoV2-induced cytokine release. Mol Syst Biol. 2021;17:e10426 pubmed publisher
Minervina A, Pogorelyy M, Kirk A, Allen E, Allison K, Lin C, et al. Convergent epitope-specific T cell responses after SARS-CoV-2 infection and vaccination. medRxiv. 2021;: pubmed publisher
Klausberger M, Duerkop M, Haslacher H, Wozniak Knopp G, Cserjan Puschmann M, Perkmann T, et al. A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests. EBioMedicine. 2021;67:103348 pubmed publisher
Cho H, Gonzales Wartz K, Huang D, Yuan M, Peterson M, Liang J, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. bioRxiv. 2021;: pubmed publisher
Anderson E, Goodwin E, Verma A, Arevalo C, Bolton M, Weirick M, et al. Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection. medRxiv. 2020;: pubmed publisher
Sun J, Liu T, Yan Y, Huo K, Zhang W, Liu H, et al. The role of Th1/Th2 cytokines played in regulation of specific CD4 + Th1 cell conversion and activation during inflammatory reaction of chronic obstructive pulmonary disease. Scand J Immunol. 2018;88:e12674 pubmed publisher
image
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Sino Biological 40605-V08B image 1
product information
Catalog Number :
40605-V08B
Product Name :
Human coronavirus (HCoV-229E) Spike Protein (S1+S2 ECD, His Tag)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
APT69883.1
Product Description :
A DNA sequence encoding the human coronavirus (HCoV-229E) spike protein (S1+S2 ECD) (APT69883.1) (Cys16-Trp1115) was expressed with a polyhistidine tag at the C-terminus.
SpeciesSummary :
HCoV-229E
ALTnames :
Spike
Purity :
> 85 % as determined by SDS-PAGE.
Buffer :
Lyophilized from sterile 20 mM PB, 300 mM NaCl, 10 % glycerol, pH 7.5
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.