product summary
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company name :
Sino Biological
product type :
protein
product name :
SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombinant Protein
catalog :
40592-V08H8
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 12
Reference
Lee J, Lee Y, Lee S, Kim J, Lee C, Kim N, et al. Versatile role of ACE2-based biosensors for detection of SARS-CoV-2 variants and neutralizing antibodies. Biosens Bioelectron. 2022;203:114034 pubmed publisher
Yuan T, Garg P, Wang L, Willis J, Kwan E, Hernandez A, et al. Rapid discovery of diverse neutralizing SARS-CoV-2 antibodies from large-scale synthetic phage libraries. MAbs. 2022;14:2002236 pubmed publisher
Bahnan W, Wrighton S, Sundwall M, Bläckberg A, Larsson O, Höglund U, et al. Spike-Dependent Opsonization Indicates Both Dose-Dependent Inhibition of Phagocytosis and That Non-Neutralizing Antibodies Can Confer Protection to SARS-CoV-2. Front Immunol. 2021;12:808932 pubmed publisher
Lin W, Chen I, Chen H, Lee Y, Wu S. Glycan Masking of Epitopes in the NTD and RBD of the Spike Protein Elicits Broadly Neutralizing Antibodies Against SARS-CoV-2 Variants. Front Immunol. 2021;12:795741 pubmed publisher
Vanhove B, Marot S, So R, Gaborit B, Evanno G, Malet I, et al. XAV-19, a Swine Glyco-Humanized Polyclonal Antibody Against SARS-CoV-2 Spike Receptor-Binding Domain, Targets Multiple Epitopes and Broadly Neutralizes Variants. Front Immunol. 2021;12:761250 pubmed publisher
Kim S, Liu Y, Lei Z, Dicker J, Cao Y, Zhang X, et al. Differential Interactions between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern. J Chem Theory Comput. 2021;17:7972-7979 pubmed publisher
Puligedda R, Al Saleem F, Wirblich C, Kattala C, Jovic M, Geiszler L, et al. A Strategy to Detect Emerging Non-Delta SARS-CoV-2 Variants with a Monoclonal Antibody Specific for the N501 Spike Residue. Diagnostics (Basel). 2021;11: pubmed publisher
Caohuy H, Eidelman O, Chen T, Liu S, Yang Q, Bera A, et al. Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells. Sci Rep. 2021;11:22195 pubmed publisher
Ravichandran S, Grubbs G, Tang J, Lee Y, Huang C, Golding H, et al. Systemic and mucosal immune profiling in asymptomatic and symptomatic SARS-CoV-2-infected individuals reveal unlinked immune signatures. Sci Adv. 2021;7:eabi6533 pubmed publisher
Yue S, Li Z, Lin Y, Yang Y, Yuan M, Pan Z, et al. Sensitivity of SARS-CoV-2 Variants to Neutralization by Convalescent Sera and a VH3-30 Monoclonal Antibody. Front Immunol. 2021;12:751584 pubmed publisher
Tang J, Lee Y, Ravichandran S, Grubbs G, Huang C, Stauft C, et al. Epitope diversity of SARS-CoV-2 hyperimmune intravenous human immunoglobulins and neutralization of variants of concern. iScience. 2021;24:103006 pubmed publisher
Guo Y, Huang L, Zhang G, Yao Y, Zhou H, Shen S, et al. A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun. 2021;12:2623 pubmed publisher
image
image 1 :
Sino Biological 40592-V08H8 image 1
product information
Catalog Number :
40592-V08H8
Product Name :
SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombinant Protein
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
YP_009724390.1
Product Description :
A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) Spike RBD(G476S)-His Recombinant Protein (YP_009724390.1) (Arg319-Phe541(G476S)) was expressed with a polyhistidine tag at the C-terminus.
SpeciesSummary :
SARS-CoV-2
ALTnames :
Spike
Purity :
> 95 % as determined by SDS-PAGE.
Buffer :
Lyophilized from sterile PBS,pH 7.4
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.