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company name :
Sino Biological
product type :
protein
product name :
SARS-CoV-2 B.1.1.529 (Omicron) Spike RBD Protein (His Tag) (HPLC-verified)
catalog :
40592-V08H121
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 23
Reference
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Hofstee M, Kaczorowska J, Postema A, Zomer E, van Waalwijk M, Jonathans G, et al. High SARS-CoV-2 antibody levels after three consecutive BNT162b2 booster vaccine doses in nursing home residents. Immun Ageing. 2025;22:1 pubmed publisher
Pinto P, Timis J, Chuensirikulchai K, Li Q, Lu H, Maule E, et al. Co-immunization with spike and nucleocapsid based DNA vaccines for long-term protective immunity against SARS-CoV-2 Omicron. NPJ Vaccines. 2024;9:252 pubmed publisher
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Garc xed a Silva I, Farf xe1 n Castro S, Rosales Mendoza S, Palestino G. Synthesis and Characterization of Thiolated Nanoparticles Based on Poly (Acrylic Acid) and Algal Cell Wall Biopolymers for the Delivery of the Receptor Binding Domain from SARS-CoV-2. Pharmaceutics. 2024;16: pubmed publisher
Chiu C, Tsai H, Chen J, Hu C, Chen H. An Immunoreceptor-Targeting Strategy with Minimalistic C3b Peptide Fusion Enhances SARS-CoV-2 RBD mRNA Vaccine Immunogenicity. Int J Nanomedicine. 2024;19:7201-7214 pubmed publisher
Poulakou G, Royer P, Evgeniev N, Evanno G, Shneiker F, Marcelin A, et al. Anti-SARS-CoV-2 glyco-humanized polyclonal antibody XAV-19: phase II/III randomized placebo-controlled trial shows acceleration to recovery for mild to moderate patients with COVID-19. Front Immunol. 2024;15:1330178 pubmed publisher
Park S, Choi J, Lee Y, Noh J, Kim N, Lee J, et al. An ancestral SARS-CoV-2 vaccine induces anti-Omicron variants antibodies by hypermutation. Nat Commun. 2024;15:3368 pubmed publisher
Yang M, Li C, Ye G, Shen C, Shi H, Zhong L, et al. Aptamers targeting SARS-CoV-2 nucleocapsid protein exhibit potential anti pan-coronavirus activity. Signal Transduct Target Ther. 2024;9:40 pubmed publisher
Wang Y, Yan A, Song D, Duan M, Dong C, Chen J, et al. Identification of a highly conserved neutralizing epitope within the RBD region of diverse SARS-CoV-2 variants. Nat Commun. 2024;15:842 pubmed publisher
Verstraete M, Heinkel F, Li J, Cao S, Tran A, Halverson E, et al. Multivalent IgM scaffold enhances the therapeutic potential of variant-agnostic ACE2 decoys against SARS-CoV-2. MAbs. 2023;15:2212415 pubmed publisher
Carlson E, Macsai M, Bertrand S, Bertrand D, Nau J. The SARS-CoV-2 Virus and the Cholinergic System: Spike Protein Interaction with Human Nicotinic Acetylcholine Receptors and the Nicotinic Agonist Varenicline. Int J Mol Sci. 2023;24: pubmed publisher
Emmenegger M, Worth R, Fiedler S, Devenish S, Knowles T, Aguzzi A. Protocol to determine antibody affinity and concentration in complex solutions using microfluidic antibody affinity profiling. STAR Protoc. 2023;4:102095 pubmed publisher
Song Z, Luo Q, Wan L, Zhu Q, Liu R, Yin X, et al. Analysis of Antibodies Induced after SARS-CoV-2 Vaccination Using Antigen Coded Bead Array Luminex Technology. Vaccines (Basel). 2023;11: pubmed publisher
Saville J, Mannar D, Zhu X, Berezuk A, Cholak S, Tuttle K, et al. Structural analysis of receptor engagement and antigenic drift within the BA.2 spike protein. Cell Rep. 2023;42:111964 pubmed publisher
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image 1 :
Sino Biological 40592-V08H121 image 1
product information
Catalog Number :
40592-V08H121
Product Name :
SARS-CoV-2 B.1.1.529 (Omicron) Spike RBD Protein (His Tag) (HPLC-verified)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
YP_009724390.1
Product Description :
A DNA sequence encoding the SARS-CoV-2 Spike RBD (YP_009724390.1, with mutation G339D, S371L, S373P, S375F, K417N, N440K, G446S, S477N, T478K, E484A, Q493R, G496S, Q498R, N501Y, Y505H) (Arg319-Phe541) was expressed with a polyhistidine tag at the C-terminus. The mutations were identified in the SARS-CoV-2 variant (known as variant B.1.1.529) which emerged in the South Africa.
SpeciesSummary :
SARS-CoV-2
ALTnames :
Spike
Purity :
> 95 % as determined by SDS-PAGE. > 95 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.