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company name :
Sino Biological
product type :
antibody
product name :
SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody, Mouse Mab
catalog :
40592-MM57
quantity :
100 µg
price :
500 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
57
reactivity :
SARS-CoV-2, SARS coronavirus, mouse
application :
ELISA, immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 25
Published Application/Species/Sample/DilutionReference
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Qin Z, Zhang K, He P, Zhang X, Xie M, Fu Y, et al. Discovering covalent inhibitors of protein-protein interactions from trillions of sulfur(VI) fluoride exchange-modified oligonucleotides. Nat Chem. 2023;: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Gomes M, Linhares J, Dos Santos T, Pereira R, Santos R, da Silva S, et al. Inactivated and Immunogenic SARS-CoV-2 for Safe Use in Immunoassays and as an Immunization Control for Non-Clinical Trials. Viruses. 2023;15: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Vanhulle E, Doijen J, Stroobants J, Provinciael B, Noppen S, Schols D, et al. Cellular electrical impedance to profile SARS-CoV-2 fusion inhibitors and to assess the fusogenic potential of spike mutants. Antiviral Res. 2023;213:105587 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Jang H, Zhuang W, Sui X, Ryu B, Huang X, Chen M, et al. Rapid, Sensitive, Label-Free Electrical Detection of SARS-CoV-2 in Nasal Swab Samples. ACS Appl Mater Interfaces. 2023;15:15195-15202 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Lu S, Mattox A, Aitana Azurmendi P, Christodoulou I, Wright K, Popoli M, et al. The rapid and highly parallel identification of antibodies with defined biological activities by SLISY. Nat Commun. 2023;14:17 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Yang C, Li D, Wang S, Xu M, Wang D, Li X, et al. Inhibitory activities of alginate phosphate and sulfate derivatives against SARS-CoV-2 in vitro. Int J Biol Macromol. 2023;227:316-328 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Pereira de Jesus B, Gomes A, Clark A, Rodrigues T, Ledgerwood Lee M, Van Zant W, et al. In Vitro Diagnostic Assay to Detect SARS-CoV-2-Neutralizing Antibody in Patient Sera Using Engineered ACE-2 Mini-Protein. Viruses. 2022;14: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Jang H, Sui X, Zhuang W, Huang X, Chen M, Cai X, et al. Remote Floating-Gate Field-Effect Transistor with 2-Dimensional Reduced Graphene Oxide Sensing Layer for Reliable Detection of SARS-CoV-2 Spike Proteins. ACS Appl Mater Interfaces. 2022;14:24187-24196 pubmed publisher
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Sølund C, Underwood A, Fernandez Antunez C, Bollerup S, Mikkelsen L, Villadsen S, et al. Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA-mRNA or Vector-mRNA COVID-19 Vaccines. Vaccines (Basel). 2022;10: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
Vanderheijden N, Stevaert A, Xie J, Ren X, Barbezange C, Noppen S, et al. Functional Analysis of Human and Feline Coronavirus Cross-Reactive Antibodies Directed Against the SARS-CoV-2 Fusion Peptide. Front Immunol. 2021;12:790415 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Heggestad J, Britton R, Kinnamon D, Wall S, Joh D, Hucknall A, et al. Rapid test to assess the escape of SARS-CoV-2 variants of concern. Sci Adv. 2021;7:eabl7682 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
Asaka M, Utsumi D, Kamada H, Nagata S, Nakachi Y, Yamaguchi T, et al. Highly susceptible SARS-CoV-2 model in CAG promoter-driven hACE2-transgenic mice. JCI Insight. 2021;6: pubmed publisher
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Underwood A, Sølund C, Fernandez Antunez C, Villadsen S, Winckelmann A, Bollerup S, et al. Neutralisation titres against SARS-CoV-2 are sustained 6 months after onset of symptoms in individuals with mild COVID-19. EBioMedicine. 2021;71:103519 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
Liu J, Chen X, Liu Y, Lin J, Shen J, Zhang H, et al. Characterization of SARS-CoV-2 worldwide transmission based on evolutionary dynamics and specific viral mutations in the spike protein. Infect Dis Poverty. 2021;10:112 pubmed publisher
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Zhao M, Su P, Castro D, Tripler T, Hu Y, Cook M, et al. Rapid, reliable, and reproducible cell fusion assay to quantify SARS-Cov-2 spike interaction with hACE2. PLoS Pathog. 2021;17:e1009683 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
Ramírez S, Fernandez Antunez C, Galli A, Underwood A, Pham L, Ryberg L, et al. Overcoming Culture Restriction for SARS-CoV-2 in Human Cells Facilitates the Screening of Compounds Inhibiting Viral Replication. Antimicrob Agents Chemother. 2021;65:e0009721 pubmed publisher
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Li Y, Ma P, Tao Q, Krause H, Yang S, Ding G, et al. Magnetic graphene quantum dots facilitate closed-tube one-step detection of SARS-CoV-2 with ultra-low field NMR relaxometry. Sens Actuators B Chem. 2021;337:129786 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Azad T, Singaravelu R, Taha Z, Jamieson T, Boulton S, Crupi M, et al. Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. Mol Ther. 2021;29:1984-2000 pubmed publisher
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Azad T, Singaravelu R, Crupi M, Jamieson T, Dave J, Brown E, et al. Implications for SARS-CoV-2 Vaccine Design: Fusion of Spike Glycoprotein Transmembrane Domain to Receptor-Binding Domain Induces Trimerization. Membranes (Basel). 2020;10: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
  • flow cytometry; mouse
  • neutralization; mouse
  • immunocytochemistry; mouse
  • ELISA; mouse
Gorshkov K, Susumu K, Chen J, Xu M, Pradhan M, Zhu W, et al. Quantum Dot-Conjugated SARS-CoV-2 Spike Pseudo-Virions Enable Tracking of Angiotensin Converting Enzyme 2 Binding and Endocytosis. ACS Nano. 2020;14:12234-12247 pubmed publisher
W xf8 rzner K, Schmidt S, Zimmermann J, Tami A, Polacek C, Fernandez Antunez C, et al. Intranasal recombinant protein subunit vaccine targeting TLR3 induces respiratory tract IgA and CD8 T cell responses and protects against respiratory virus infection. EBioMedicine. 2025;113:105615 pubmed publisher
Li H, Gong H, Wong T, Zhou J, Wang Y, Lin L, et al. Wireless, battery-free, multifunctional integrated bioelectronics for respiratory pathogens monitoring and severity evaluation. Nat Commun. 2023;14:7539 pubmed publisher
Hunt A, V xf6 geli B, Hassan A, Guerrero L, Kightlinger W, Yoesep D, et al. A rapid cell-free expression and screening platform for antibody discovery. Nat Commun. 2023;14:3897 pubmed publisher
Ham Y, Cho N, Kim D, Kim J, Jo M, Jeong M, et al. The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction. Biosens Bioelectron. 2023;227:115169 pubmed publisher
Azad T, Singaravelu R, Brown E, Taha Z, Rezaei R, Arulanandam R, et al. SARS-CoV-2 S1 NanoBiT: A nanoluciferase complementation-based biosensor to rapidly probe SARS-CoV-2 receptor recognition. Biosens Bioelectron. 2021;180:113122 pubmed publisher
image
image 1 :
Sino Biological 40592-MM57 image 1
product information
Catalog Number :
40592-MM57
Product Name :
SARS-CoV-2 (2019-nCoV) Spike Neutralizing Antibody, Mouse Mab
Product Type :
Antibody
Host Species :
Mouse
Clonality :
monoclonal
Conjugation :
Unconjugated
Isotype :
IgG2b
Size :
100 µg
List Price :
500 USD
Gene ID :
57
Product Description :
This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD-mFc Protein (Catalog#40592-V05H; YP_009724390.1; Arg319-Phe541). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
SpeciesSummary :
SARS-CoV-2
ALTnames :
Spike
Immunogen :
Recombinant SARS-CoV-2 (2019-nCoV) Spike RBD-mFc Protein (Catalog#40592-V05H)
Purity :
protein A
Buffer :
25 mM Sodium Citrate, 200 mM NaCl, 0.02% Tween-80, pH 6.0
Application Summary :
ELISA,FCM,ICC/IF,Neutralization
Storage :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.