product summary
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company name :
Sino Biological
product type :
protein
product name :
SARS-CoV-2 (2019-nCoV) Spike S1-Fc Recombinant Protein
catalog :
40591-V02H
quantity :
100 µg
price :
498 USD
more info or order :
Sino Biological product webpage
citations: 15
Reference
Kim Y, Park I, Shin J, Choi J, Jeon C, Jeon S, et al. Sublingual Dissolving Microneedle (SLDMN)-Based Vaccine for Inducing Mucosal Immunity against SARS-CoV-2. Adv Healthc Mater. 2023;:e2300889 pubmed publisher
Mudrick H, Massey S, McGlinch E, Parrett B, Hemsath J, Barry M, et al. Comparison of replicating and nonreplicating vaccines against SARS-CoV-2. Sci Adv. 2022;8:eabm8563 pubmed publisher
Hirano M, Ando R, Shimozono S, Sugiyama M, Takeda N, Kurokawa H, et al. A highly photostable and bright green fluorescent protein. Nat Biotechnol. 2022;40:1132-1142 pubmed publisher
Caohuy H, Eidelman O, Chen T, Liu S, Yang Q, Bera A, et al. Common cardiac medications potently inhibit ACE2 binding to the SARS-CoV-2 Spike, and block virus penetration and infectivity in human lung cells. Sci Rep. 2021;11:22195 pubmed publisher
Lallow E, Jhumur N, Ahmed I, Kudchodkar S, Roberts C, Jeong M, et al. Novel suction-based in vivo cutaneous DNA transfection platform. Sci Adv. 2021;7:eabj0611 pubmed publisher
Sun Y, Zhou J, Zhu H, Xu F, Zhao W, Lu H, et al. Development of a Recombinant RBD Subunit Vaccine for SARS-CoV-2. Viruses. 2021;13: pubmed publisher
Zhang F, Li W, Feng J, Ramos da Silva S, Ju E, Zhang H, et al. SARS-CoV-2 pseudovirus infectivity and expression of viral entry-related factors ACE2, TMPRSS2, Kim-1, and NRP-1 in human cells from the respiratory, urinary, digestive, reproductive, and immune systems. J Med Virol. 2021;93:6671-6685 pubmed publisher
Ouyang W, Xie T, Fang H, Gao C, Stantchev T, Clouse K, et al. Variable Induction of Pro-Inflammatory Cytokines by Commercial SARS CoV-2 Spike Protein Reagents: Potential Impacts of LPS on In Vitro Modeling and Pathogenic Mechanisms In Vivo. Int J Mol Sci. 2021;22: pubmed publisher
Song D, Wang W, Dong C, Ning Z, Liu X, Liu C, et al. Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2. Commun Biol. 2021;4:500 pubmed publisher
Ren W, Zhu Y, Wang Y, Shi H, Yu Y, Hu G, et al. Comparative analysis reveals the species-specific genetic determinants of ACE2 required for SARS-CoV-2 entry. PLoS Pathog. 2021;17:e1009392 pubmed publisher
Bertoglio F, Meier D, Langreder N, Steinke S, Rand U, Simonelli L, et al. SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface. Nat Commun. 2021;12:1577 pubmed publisher
Bhattacharjee M, Lin J, Chang C, Chiou Y, Li T, Tai C, et al. Identifying Primate ACE2 Variants That Confer Resistance to SARS-CoV-2. Mol Biol Evol. 2021;38:2715-2731 pubmed publisher
Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, et al. A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry. Nat Commun. 2021;12:961 pubmed publisher
Jin W, Zhang W, Mitra D, McCandless M, Sharma P, Tandon R, et al. The structure-activity relationship of the interactions of SARS-CoV-2 spike glycoproteins with glucuronomannan and sulfated galactofucan from Saccharina japonica. Int J Biol Macromol. 2020;163:1649-1658 pubmed publisher
Wang C, Xie J, Zhao L, Fei X, Zhang H, Tan Y, et al. Alveolar macrophage dysfunction and cytokine storm in the pathogenesis of two severe COVID-19 patients. EBioMedicine. 2020;57:102833 pubmed publisher
image
image 1 :
Sino Biological 40591-V02H image 1
product information
Catalog Number :
40591-V02H
Product Name :
SARS-CoV-2 (2019-nCoV) Spike S1-Fc Recombinant Protein
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-human IgG1-Fc
Size :
100 µg
List Price :
498 USD
Gene ID :
YP_009724390.1
Product Description :
A DNA sequence encoding the SARS-CoV-2 (2019-nCoV) spike protein S1 Subunit (YP_009724390.1) (Val16-Arg685) was expressed with the Fc region of human IgG1 at the C-terminus.
SpeciesSummary :
SARS-CoV-2
ALTnames :
Spike
Purity :
> 90 % as determined by SDS-PAGE.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.