product summary
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company name :
Sino Biological
product type :
antibody
product name :
SARS-CoV-2 (2019-nCoV) Spike Antibody, Rabbit PAb, Antigen Affinity Purified
catalog :
40591-T62
quantity :
100 µL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
SARS coronavirus
application :
western blot, ELISA
more info or order :
citations: 34
Published Application/Species/Sample/DilutionReference
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Hu Y, Zou J, Nguyen M, Chang H, Yeung J, Hao H, et al. Comparative analysis of replication and immune evasion among SARS-CoV-2 subvariants BA.2.86, JN.1, KP.2, and KP.3. MBio. 2025;16:e0350324 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Dong D, Song Y, Wu S, Wang B, Peng C, Zhang W, et al. Molecular basis of Ad5-nCoV vaccine-induced immunogenicity. Structure. 2025;33:858-868.e5 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Ma R, Zhang X, Li R, Dong X, Wang W, Jiang Q, et al. PLSCR1 suppresses SARS-CoV-2 infection by downregulating cell surface ACE2. J Virol. 2025;99:e0208524 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Edeling M, Earnest L, Carrera Montoya J, Yap A, Mumford J, Roberts J, et al. Development of Methods to Produce SARS CoV-2 Virus-Like Particles at Scale. Biotechnol Bioeng. 2025;122:1118-1129 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Tieu K, Espey M, Narayanan A, Heise R, Alem F, Conway D. SARS-CoV-2 S-protein expression drives syncytia formation in endothelial cells. Sci Rep. 2025;15:3549 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Mendes S, Guimar xe3 es L, de Oliveira L, Costa P, da Silva N, Pereira G, et al. Intranasal liposomal remdesivir induces SARS-CoV-2 clearance in K18-hACE2 mice and ensures survival. J Control Release. 2025;379:558-573 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Abt E, Lam A, Noguchi M, Rashid k, McLaughlin J, Teng P, et al. Staggered immunization with mRNA vaccines encoding SARS-CoV-2 polymerase or spike antigens broadens the T cell epitope repertoire. Proc Natl Acad Sci U S A. 2024;121:e2406332121 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Mendes S, Guimar xe3 es L, Costa P, Fernandez C, Figueiredo M, Teixeira M, et al. Intranasal liposomal angiotensin-(1-7) administration reduces inflammation and viral load in the lungs during SARS-CoV-2 infection in K18-hACE2 transgenic mice. Antimicrob Agents Chemother. 2024;68:e0083524 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Liu Y, Zhao X, Shi J, Wang Y, Liu H, Hu Y, et al. Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3. Nat Commun. 2024;15:8728 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Emam M, Mahmoud M, El Guendy N, Loutfy S. Establishment of in-house assay for screening of anti-SARS-CoV-2 protein inhibitors. AMB Express. 2024;14:104 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Deng J, Yang S, Li Y, Tan X, Liu J, Yu Y, et al. Natural evidence of coronaviral 2'-O-methyltransferase activity affecting viral pathogenesis via improved substrate RNA binding. Signal Transduct Target Ther. 2024;9:140 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Hong W, Lei H, Peng D, Huang Y, He C, Yang J, et al. A chimeric adenovirus-vectored vaccine based on Beta spike and Delta RBD confers a broad-spectrum neutralization against Omicron-included SARS-CoV-2 variants. MedComm (2020). 2024;5:e539 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Kim D, Kim M, Kim J, Baek K, Park H, Park S, et al. A mouse xenograft long-term replication yields a SARS-CoV-2 Delta mutant with increased lethality. J Med Virol. 2024;96:e29459 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Guimarães L, Costa P, Scalzo J xfa nior S, Ferreira H, Braga A, de Oliveira L, et al. Nanoparticle-based DNA vaccine protects against SARS-CoV-2 variants in female preclinical models. Nat Commun. 2024;15:590 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Kim D, Kim J, Kim M, Park H, Park S, Maharjan S, et al. Analysis of spike protein variants evolved in a novel in vivo long-term replication model for SARS-CoV-2. Front Cell Infect Microbiol. 2023;13:1280686 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Liu L, Casner R, Guo Y, Wang Q, Iketani S, Chan J, et al. Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Immunity. 2023;56:2442-2455.e8 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Qu P, Xu K, Faraone J, Goodarzi N, Zheng Y, Carlin C, et al. Immune Evasion, Infectivity, and Fusogenicity of SARS-CoV-2 Omicron BA.2.86 and FLip Variants. bioRxiv. 2023;: pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Wu X, Shan K, Zan F, Tang X, Qian Z, Lu J. Optimization and Deoptimization of Codons in SARS-CoV-2 and Related Implications for Vaccine Development. Adv Sci (Weinh). 2023;10:e2205445 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Yurkovetskiy L, Egri S, Kurhade C, Díaz Salinas M, Jaimes J, Nyalile T, et al. S:D614G and S:H655Y are gateway mutations that act epistatically to promote SARS-CoV-2 variant fitness. bioRxiv. 2023;: pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Dong W, Wang J, Tian L, Zhang J, Settles E, Qin C, et al. Factor Xa cleaves SARS-CoV-2 spike protein to block viral entry and infection. Nat Commun. 2023;14:1936 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Chen K, Shi D, Li C, Fang Z, Guo Y, Jiang W, et al. Adenovirus Vaccine Containing Truncated SARS-CoV-2 Spike Protein S1 Subunit Leads to a Specific Immune Response in Mice. Vaccines (Basel). 2023;11: pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Qu P, Faraone J, Evans J, Zheng Y, Carlin C, Anghelina M, et al. Extraordinary Evasion of Neutralizing Antibody Response by Omicron XBB.1.5, CH.1.1 and CA.3.1 Variants. bioRxiv. 2023;: pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Seo S, Ryu E, Kim J, Shin C, Kwon O. Fluorophore-encapsulated nanobeads for on-site, rapid, and sensitive lateral flow assay. Sens Actuators B Chem. 2023;381:133364 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Cooper A, Sidaway A, Chandrashekar A, Latta E, Chakraborty K, Yu J, et al. A genetically engineered, stem-cell-derived cellular vaccine. Cell Rep Med. 2022;3:100843 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Frolova E, Palchevska O, Lukash T, Dominguez F, Britt W, Frolov I. Acquisition of Furin Cleavage Site and Further SARS-CoV-2 Evolution Change the Mechanisms of Viral Entry, Infection Spread, and Cell Signaling. J Virol. 2022;96:e0075322 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Lubinski B, Frazier L, Phan M, Bugembe D, Cunningham J, Tang T, et al. Spike Protein Cleavage-Activation in the Context of the SARS-CoV-2 P681R Mutation: an Analysis from Its First Appearance in Lineage A.23.1 Identified in Uganda. Microbiol Spectr. 2022;10:e0151422 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Haga K, Takai Todaka R, Sawada A, Katayama K. Luciferase-based quantification of membrane fusion induced by SARS-CoV-2 S protein. Genes Cells. 2022;27:537-543 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Cao K, Wang X, Peng H, Ding L, Wang X, Hu Y, et al. A Single Vaccine Protects against SARS-CoV-2 and Influenza Virus in Mice. J Virol. 2022;96:e0157821 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Zhang Y, Shang L, Zhang J, Liu Y, Jin C, Zhao Y, et al. An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity. Cell Chem Biol. 2022;29:5-18.e6 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Shao L, Ning K, Wang J, Cheng F, Wang S, Qiu J. The large nonstructural protein (NS1) of the human bocavirus 1 (HBoV1) directly interacts with Ku70, which plays an important role in virus replication in human airway epithelia. J Virol. 2021;:JVI0184021 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Ohtsuka J, Imai M, Fukumura M, Maeda M, Eguchi A, Ono R, et al. Non-propagative human parainfluenza virus type 2 nasal vaccine robustly protects the upper and lower airways against SARS-CoV-2. iScience. 2021;24:103379 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Wang Q, Nair M, Anang S, Zhang S, Nguyen H, Huang Y, et al. Functional differences among the spike glycoproteins of multiple emerging severe acute respiratory syndrome coronavirus 2 variants of concern. iScience. 2021;24:103393 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
He X, Ding L, Cao K, Peng H, Gu C, Li Y, et al. A human cell-based SARS-CoV-2 vaccine elicits potent neutralizing antibody responses and protects mice from SARS-CoV-2 challenge. Emerg Microbes Infect. 2021;10:1555-1573 pubmed publisher
  • ELISA; SARS coronavirus
  • western blot; SARS coronavirus
Prahlad J, Struble L, Lutz W, Wallin S, Khurana S, Schnaubelt A, et al. CyDisCo production of functional recombinant SARS-CoV-2 spike receptor binding domain. Protein Sci. 2021;: pubmed publisher
product information
Catalog Number :
40591-T62
Product Name :
SARS-CoV-2 (2019-nCoV) Spike Antibody, Rabbit PAb, Antigen Affinity Purified
Product Type :
Antibody
Host Species :
Rabbit
Clonality :
polyclonal
Isotype :
IgG
Size :
100 µL
List Price :
299 USD
Product Description :
Produced in rabbits immunized with purified, recombinant SARS-CoV-2 (2019-nCoV) Spike S1-His Recombiant Protein (HPLC-verified) (Catalog#40591-V08H; YP_009724390.1; Val16-Arg685). The specific IgG was purified by SARS-CoV-2 / 2019-nCoV Spike affinity chromatography.
SpeciesSummary :
SARS-CoV-2
ALTnames :
CXCL16,CXCLG16,SRPSOX,SR-PSOX,SCYB16,UNQ2759/PRO6714,0910001K24Rik,b2b498Clo,CXCL16v1,CXCL16v2,Zmynd15
Immunogen :
Recombinant SARS-CoV-2 (2019-nCoV) Spike S-His Protein (Catalog#40591-V08H)
Purity :
Protein A & Antigen Affinity
Buffer :
0.2 μm filtered solution in PBS
Application Summary :
WB,ELISA
Storage :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.