SARS-CoV-2 (2019-nCoV) Spike S2 Antibody, Rabbit PAb, Antigen Affinity Purified | Sino Biological 40590-T62 product information

product summary

company name :

Sino Biological

product type :

antibody

product name :

SARS-CoV-2 (2019-nCoV) Spike S2 Antibody, Rabbit PAb, Antigen Affinity Purified

catalog :

40590-T62

quantity :

100 µL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

SARS coronavirus, SARS-CoV-2, domestic rabbit

application :

western blot, ELISA

more info or order :

Sino Biological product webpage

citations: 41

Published Application/Species/Sample/Dilution	Reference
ELISA; SARS coronavirus western blot; SARS coronavirus	Wang J, Ma Y, Li Z, Yuan H, Liu B, Li Z, et al. SARS-related coronavirus S-protein structures reveal synergistic RBM interactions underpinning high-affinity human ACE2 binding. Sci Adv. 2025;11:eadr8772 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Adeleke R, Sahler J, Choi A, Roth K, Upadhye V, Ezzatpour S, et al. Replication-incompetent VSV-based vaccine elicits protective responses against SARS-CoV-2 and influenza virus. Sci Adv. 2025;11:eadq4545 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Ojha R, Jiang A, M xe4 ntyl xe4 E, Quirin T, Modhira N, Witte R, et al. Dynamin independent endocytosis is an alternative cell entry mechanism for multiple animal viruses. PLoS Pathog. 2024;20:e1012690 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Asgharian H, Kammarchedu V, Soltan Khamsi P, Brustoloni C, Ebrahimi A. Multi-Electrode Extended Gate Field Effect Transistors Based on Laser-Induced Graphene for the Detection of Vitamin C and SARS-CoV-2. ACS Appl Mater Interfaces. 2024;16:63142-63154 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Dey S, Pahari P, Mukherjee S, Munro J, Das D. Conformational dynamics of SARS-CoV-2 Omicron spike trimers during fusion activation at single molecule resolution. Structure. 2024;32:1910-1925.e6 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Su W, Ahmad I, Wu Y, Tang L, Khan I, Ye B, et al. Furin Egress from the TGN is Regulated by Membrane-Associated RING-CH Finger (MARCHF) Proteins and Ubiquitin-Specific Protease 32 (USP32) via Nondegradable K33-Polyubiquitination. Adv Sci (Weinh). 2024;11:e2403732 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	P xe9 rez Vargas J, Lemieux G, Thompson C, D xe9 silets A, Ennis S, Gao G, et al. Nanomolar anti-SARS-CoV-2 Omicron activity of the host-directed TMPRSS2 inhibitor N-0385 and synergistic action with direct-acting antivirals. Antiviral Res. 2024;225:105869 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Qu P, Xu K, Faraone J, Goodarzi N, Zheng Y, Carlin C, et al. Immune evasion, infectivity, and fusogenicity of SARS-CoV-2 BA.2.86 and FLip variants. Cell. 2024;187:585-595.e6 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Fan J, Li S, Zhang Y, Zheng J, Wang D, Liao Y, et al. Early Emerging SARS-CoV-2 Spike Mutants Are Diversified in Virologic Properties but Elicit Compromised Antibody Responses. Viruses. 2023;15: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	H xe4 ring C, Jungwirth J, Schroeder J, L xf6 ffler B, Engert B, Ehrhardt C. The Local Anaesthetic Procaine Prodrugs ProcCluster® and Procaine Hydrochloride Impair SARS-CoV-2 Replication and Egress In Vitro. Int J Mol Sci. 2023;24: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Greene K, Choi A, Chen M, Yang N, Li R, Qiu Y, et al. Inhibiting Glutamine Metabolism Blocks Coronavirus Replication in Mammalian Cells. bioRxiv. 2023;: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Liu L, Casner R, Guo Y, Wang Q, Iketani S, Chan J, et al. Antibodies targeting a quaternary site on SARS-CoV-2 spike glycoprotein prevent viral receptor engagement by conformational locking. Immunity. 2023;56:2442-2455.e8 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Shuai H, Hu B, Chai Y, Yoon C, Liu H, Liu Y, et al. The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA.1, BA.2, and BA.5. EBioMedicine. 2023;95:104753 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Xu D, Jiang W, Wu L, Gaudet R, Park E, Su M, et al. PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection. Nature. 2023;619:819-827 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Qu P, Faraone J, Evans J, Zheng Y, Carlin C, Anghelina M, et al. Enhanced evasion of neutralizing antibody response by Omicron XBB.1.5, CH.1.1, and CA.3.1 variants. Cell Rep. 2023;42:112443 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Frolov I, Agback T, Palchevska O, Dominguez F, Lomzov A, Agback P, et al. All Domains of SARS-CoV-2 nsp1 Determine Translational Shutoff and Cytotoxicity of the Protein. J Virol. 2023;97:e0186522 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Qu P, Evans J, Kurhade C, Zeng C, Zheng Y, Xu K, et al. Determinants and Mechanisms of the Low Fusogenicity and High Dependence on Endosomal Entry of Omicron Subvariants. MBio. 2023;14:e0317622 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Chan J, Hu B, Chai Y, Shuai H, Liu H, Shi J, et al. Virological features and pathogenicity of SARS-CoV-2 Omicron BA.2. Cell Rep Med. 2022;3:100743 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Frolova E, Palchevska O, Lukash T, Dominguez F, Britt W, Frolov I. Acquisition of Furin Cleavage Site and Further SARS-CoV-2 Evolution Change the Mechanisms of Viral Entry, Infection Spread, and Cell Signaling. J Virol. 2022;96:e0075322 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Shuai H, Chan J, Hu B, Chai Y, Yuen T, Yin F, et al. Attenuated replication and pathogenicity of SARS-CoV-2 B.1.1.529 Omicron. Nature. 2022;603:693-699 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Du S, Xu W, Wang Y, Li L, Hao P, Tian M, et al. The "LLQY" Motif on SARS-CoV-2 Spike Protein Affects S Incorporation into Virus Particles. J Virol. 2022;96:e0189721 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Yu S, Zheng X, Zhou B, Li J, Chen M, Deng R, et al. SARS-CoV-2 spike engagement of ACE2 primes S2' site cleavage and fusion initiation. Proc Natl Acad Sci U S A. 2022;119: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Lubinski B, Fernandes M, Frazier L, Tang T, Daniel S, Diel D, et al. Functional evaluation of the P681H mutation on the proteolytic activation of the SARS-CoV-2 variant B.1.1.7 (Alpha) spike. iScience. 2022;25:103589 pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Wang W, Li S, Xu X, Yang C, Niu X, Yin S, et al. Danshensu alleviates pseudo-typed SARS-CoV-2 induced mouse acute lung inflammation. Acta Pharmacol Sin. 2022;43:771-780 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Lubinski B, Frazier L, Phan M, Bugumbe D, Cunningham J, Tang T, et al. Spike protein cleavage-activation mediated by the SARS-CoV-2 P681R mutation: a case-study from its first appearance in variant of interest (VOI) A.23.1 identified in Uganda. bioRxiv. 2022;: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Kim G, Choi J, Wu K, Saeedian N, Yang E, Park H, et al. A vesicular stomatitis virus-based prime-boost vaccination strategy induces potent and protective neutralizing antibodies against SARS-CoV-2. PLoS Pathog. 2021;17:e1010092 pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Mariotti S, Capocefalo A, Chiantore M, Iacobino A, Teloni R, De Angelis M, et al. Isolation and Characterization of Mouse Monoclonal Antibodies That Neutralize SARS-CoV-2 and Its Variants of Concern Alpha, Beta, Gamma and Delta by Binding Conformational Epitopes of Glycosylated RBD With High Potency. Front Immunol. 2021;12:750386 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus	Wang Q, Nair M, Anang S, Zhang S, Nguyen H, Huang Y, et al. Functional differences among the spike glycoproteins of multiple emerging severe acute respiratory syndrome coronavirus 2 variants of concern. iScience. 2021;24:103393 pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Sun D, Sang Z, Kim Y, Xiang Y, Cohen T, Belford A, et al. Potent neutralizing nanobodies resist convergent circulating variants of SARS-CoV-2 by targeting diverse and conserved epitopes. Nat Commun. 2021;12:4676 pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Sharma A, Ong J, Loke M, Chua E, Lee J, Choi H, et al. Comparative Transcriptomic and Molecular Pathway Analyses of HL-CZ Human Pro-Monocytic Cells Expressing SARS-CoV-2 Spike S1, S2, NP, NSP15 and NSP16 Genes. Microorganisms. 2021;9: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Dispinseri S, Secchi M, Pirillo M, Tolazzi M, Borghi M, Brigatti C, et al. Neutralizing antibody responses to SARS-CoV-2 in symptomatic COVID-19 is persistent and critical for survival. Nat Commun. 2021;12:2670 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Deinhardt Emmer S, Böttcher S, Häring C, Giebeler L, Henke A, Zell R, et al. SARS-CoV-2 causes severe epithelial inflammation and barrier dysfunction. J Virol. 2021;: pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Zhu Y, Feng F, Hu G, Wang Y, Yu Y, Zhu Y, et al. A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry. Nat Commun. 2021;12:961 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Tang T, Jaimes J, Bidon M, Straus M, Daniel S, Whittaker G. Proteolytic Activation of SARS-CoV-2 Spike at the S1/S2 Boundary: Potential Role of Proteases beyond Furin. ACS Infect Dis. 2021;7:264-272 pubmed publisher
western blot; SARS coronavirus; loading ...; fig s5, s7a	Chu H, Hu B, Huang X, Chai Y, Zhou D, Wang Y, et al. Host and viral determinants for efficient SARS-CoV-2 infection of the human lung. Nat Commun. 2021;12:134 pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Zang R, Case J, Yutuc E, Ma X, Shen S, Gomez Castro M, et al. Cholesterol 25-hydroxylase suppresses SARS-CoV-2 replication by blocking membrane fusion. Proc Natl Acad Sci U S A. 2020;117:32105-32113 pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Yang Q, Hughes T, Kelkar A, Yu X, Cheng K, Park S, et al. Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration. elife. 2020;9: pubmed publisher
ELISA; SARS coronavirus western blot; SARS coronavirus ELISA; domestic rabbit western blot; domestic rabbit	Takeda Y, Murata T, Jamsransuren D, Suganuma K, Kazami Y, Batkhuu J, et al. Saxifraga spinulosa-Derived Components Rapidly Inactivate Multiple Viruses Including SARS-CoV-2. Viruses. 2020;12: pubmed publisher
ELISA; domestic rabbit western blot; domestic rabbit ELISA; SARS coronavirus western blot; SARS coronavirus	Tang T, Bidon M, Jaimes J, Whittaker G, Daniel S. Coronavirus membrane fusion mechanism offers a potential target for antiviral development. Antiviral Res. 2020;178:104792 pubmed publisher
	Fahoum J, Billan M, Varga J, Padawer D, Britan Rosich Y, Elgrably Weiss M, et al. Transfer of SARS-CoV-2 nucleocapsid protein to uninfected epithelial cells induces antibody-mediated complement deposition. Cell Rep. 2025;44:115512 pubmed publisher
	Hu B, Chan J, Liu H, Liu Y, Chai Y, Shi J, et al. Spike mutations contributing to the altered entry preference of SARS-CoV-2 omicron BA.1 and BA.2. Emerg Microbes Infect. 2022;11:2275-2287 pubmed publisher

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product information

Catalog Number :

40590-T62

Product Name :

SARS-CoV-2 (2019-nCoV) Spike S2 Antibody, Rabbit PAb, Antigen Affinity Purified

Product Type :

Antibody

Host Species :

Rabbit

Clonality :

polyclonal

Conjugation :

Unconjugated

Isotype :

IgG

Size :

100 µL

List Price :

299 USD

Product Description :

Produced in rabbits immunized with recombinant SARS-CoV-2 / 2019-nCoV Spike/S2 Protein (Catalog#40590-V08B; YP_009724390.1; Ser686-Pro1213). The specific IgG was purified by SARS-CoV-2 / 2019-nCoV Spike/S2 affinity chromatography.

SpeciesSummary :

SARS-CoV-2

ALTnames :

Spike

Immunogen :

Recombinant SARS-CoV-2 / 2019-nCoV Spike/S2 Protein (Catalog#40590-V08B)

Purity :

Protein A & Antigen Affinity

Buffer :

0.2 μm filtered solution in PBS

Application Summary :

WB,ELISA

Storage :

This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage