product summary
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company name :
Sino Biological
product type :
protein
product name :
SARS-CoV Spike/RBD Protein (RBD, His Tag)
catalog :
40150-V08B2
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 18
Reference
Zhang S, Xu C, Wang J, Xiong X, Wang J. Spike proteins of coronaviruses activate mast cells for degranulation via stimulating Src/PI3K/AKT/Ca2+ intracellular signaling cascade. J Virol. 2025;99:e0007825 pubmed publisher
Yu W, Yi S, Jiang C, Guan J, Xue R, Zhang X, et al. Biosensor-based active ingredient recognition system for screening potential small molecular Severe acute respiratory syndrome coronavirus 2 entry blockers targeting the spike protein from Rugosa rose. Biomed Chromatogr. 2024;38:e5987 pubmed publisher
Kaku C, Starr T, Zhou P, Dugan H, Khalif xe9 P, Song G, et al. Evolution of antibody immunity following Omicron BA.1 breakthrough infection. Nat Commun. 2023;14:2751 pubmed publisher
Kassardjian A, Sun E, Sookhoo J, Muthuraman K, Boligan K, Kucharska I, et al. Modular adjuvant-free pan-HLA-DR-immunotargeting subunit vaccine against SARS-CoV-2 elicits broad sarbecovirus-neutralizing antibody responses. Cell Rep. 2023;42:112391 pubmed publisher
Shim J, Kim Y, Choe J, Lee T, You E. Single-Nanoparticle-Based Digital SERS Sensing Platform for the Accurate Quantitative Detection of SARS-CoV-2. ACS Appl Mater Interfaces. 2022;14:38459-38470 pubmed publisher
Koklu A, Wustoni S, Guo K, Silva R, Salvigni L, Hama A, et al. Convection Driven Ultrarapid Protein Detection via Nanobody-Functionalized Organic Electrochemical Transistors. Adv Mater. 2022;34:e2202972 pubmed publisher
Hwu A, Madadelahi M, Nakajima R, Shamloo E, Perebikovsky A, Kido H, et al. Centrifugal disc liquid reciprocation flow considerations for antibody binding to COVID antigen array during microfluidic integration. Lab Chip. 2022;22:2695-2706 pubmed publisher
Li Y, Fan Q, Zhou B, Shen Y, Zhang Y, Cheng L, et al. Structural and functional analysis of an inter-Spike bivalent neutralizing antibody against SARS-CoV-2 variants. iScience. 2022;25:104431 pubmed publisher
Brazaca L, Imamura A, Gomes N, Almeida M, Scheidt D, Raymundo Pereira P, et al. Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2. Anal Bioanal Chem. 2022;414:5507-5517 pubmed publisher
Agarwal D, Nandwana V, Henrich S, Josyula V, Thaxton C, Qi C, et al. Highly sensitive and ultra-rapid antigen-based detection of SARS-CoV-2 using nanomechanical sensor platform. Biosens Bioelectron. 2022;195:113647 pubmed publisher
Yi C, Sun X, Lin Y, Gu C, Ding L, Lu X, et al. Comprehensive mapping of binding hot spots of SARS-CoV-2 RBD-specific neutralizing antibodies for tracking immune escape variants. Genome Med. 2021;13:164 pubmed publisher
Payne T, Klawa S, Jian T, Kim S, Papanikolas M, Freeman R, et al. Catching COVID: Engineering Peptide-Modified Surface-Enhanced Raman Spectroscopy Sensors for SARS-CoV-2. ACS Sens. 2021;6:3436-3444 pubmed publisher
Zhou Z, Dharmarajan S, Lehtimäki M, Kirshner S, Kozlowski S. Early antibody responses associated with survival in COVID19 patients. PLoS Pathog. 2021;17:e1009766 pubmed publisher
Guo K, Wustoni S, Koklu A, D xed az Galicia E, Moser M, Hama A, et al. Rapid single-molecule detection of COVID-19 and MERS antigens via nanobody-functionalized organic electrochemical transistors. Nat Biomed Eng. 2021;5:666-677 pubmed publisher
Liu T, Hsiung J, Zhao S, Kost J, Sreedhar D, Hanson C, et al. Quantification of antibody avidities and accurate detection of SARS-CoV-2 antibodies in serum and saliva on plasmonic substrates. Nat Biomed Eng. 2020;4:1188-1196 pubmed publisher
Chi X, Liu X, Wang C, Zhang X, Li X, Hou J, et al. Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain. Nat Commun. 2020;11:4528 pubmed publisher
Lv Z, Deng Y, Ye Q, Cao L, Sun C, Fan C, et al. Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science. 2020;369:1505-1509 pubmed publisher
Lu J, Sun P. High affinity binding of SARS-CoV-2 spike protein enhances ACE2 carboxypeptidase activity. bioRxiv. 2020;: pubmed publisher
image
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Sino Biological 40150-V08B2 image 1
product information
Catalog Number :
40150-V08B2
Product Name :
SARS-CoV Spike/RBD Protein (RBD, His Tag)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
AAX16192.1
Product Description :
A DNA sequence encoding the receptor binding domain (RBD) of SARS-CoV (isolate:WH20) spike (AAX16192.1) (Arg306-Phe527) was expressed with a C-terminal polyhistidine tag.
SpeciesSummary :
SARS
ALTnames :
Spike
Purity :
> 95 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile 20mM PBS，300mM NaCl，10% glycerol，pH 7.0
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.