product summary
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company name :
Sino Biological
product type :
antibody
product name :
SARS-CoV / SARS-CoV-2 Spike antibody, Chimeric MAb
catalog :
40150-D001
quantity :
100 µL
price :
400 USD
clonality :
monoclonal
host :
SARS coronavirus
conjugate :
nonconjugated
clone name :
D001
reactivity :
SARS coronavirus
application :
ELISA, immunocytochemistry, neutralization, flow cytometry
more info or order :
citations: 28
Published Application/Species/Sample/DilutionReference
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Lee J, Sachithanandham J, Lee J, Shapiro J, Li M, Sitaris I, et al. A third COVID-19 vaccine dose in kidney transplant recipients induces antibody response to vaccine and Omicron variants but shows limited Ig subclass switching. Microbiol Spectr. 2025;13:e0219024 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Li J, Liu J, Wei C, Liu X, Lin S, Wu C. Hydrogel-Gated MXene-Graphene Field-Effect Transistor for Selective Detection and Screening of SARS-CoV-2 and E. coli Bacteria. ACS Appl Mater Interfaces. 2025;17:2871-2883 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Yang Y, Hu J, Deng H, Chen D, Wu G, Xing H, et al. Maternal Preconception COVID-19 Vaccination and Its Protective Effect on Infants after a Breakthrough Infection during Pregnancy. Vaccines (Basel). 2024;12: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Hsieh L, Looney M, Figueroa A, Massaccesi G, Stavrakis G, Anaya E, et al. Bystander monocytic cells drive infection-independent NLRP3 inflammasome response to SARS-CoV-2. MBio. 2024;15:e0081024 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
St Clair L, Eldesouki R, Sachithanandham J, Yin A, Fall A, Morris C, et al. Reduced control of SARS-CoV-2 infection associates with lower mucosal antibody responses in pregnancy. mSphere. 2024;9:e0081223 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Clair L, Eldesouki R, Sachithanandham J, Yin A, Fall A, Morris C, et al. Reduced control of SARS-CoV-2 infection is associated with lower mucosal antibody responses in pregnant women. medRxiv. 2023;: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Fossat N, Lundsgaard E, Costa R, Rivera Rangel L, Nielsen L, Mikkelsen L, et al. Identification of the viral and cellular microRNA interactomes during SARS-CoV-2 infection. Cell Rep. 2023;42:112282 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Hora B, Li H, Shen X, Martin M, Chen Y, Berry M, et al. Neonatal SHIV infection in rhesus macaques elicited heterologous HIV-1-neutralizing antibodies. Cell Rep. 2023;42:112255 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Yang Y, Xing H, Zhao Y. Transplacental transmission of SARS-CoV-2 immunoglobulin G antibody to infants from maternal COVID-19 vaccine immunization before pregnancy. J Med Virol. 2023;95:e28296 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Jiang Y, Deng Y, Pang H, Ma T, Ye Q, Chen Q, et al. Treatment of SARS-CoV-2-induced pneumonia with NAD+ and NMN in two mouse models. Cell Discov. 2022;8:38 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Su W, Du P, Santos H, Ho T, Keskin B, Pau C, et al. Antibody Profiling in COVID-19 Patients with Different Severities by Using Spike Variant Protein Microarrays. Anal Chem. 2022;94:6529-6539 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Ho T, Du P, Su W, Santos H, Lin Y, Chou Y, et al. Development of SARS-CoV-2 variant protein microarray for profiling humoral immunity in vaccinated subjects. Biosens Bioelectron. 2022;204:114067 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Heggestad J, Britton R, Kinnamon D, Wall S, Joh D, Hucknall A, et al. Rapid test to assess the escape of SARS-CoV-2 variants of concern. Sci Adv. 2021;7:eabl7682 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
White I, Tamot N, Doddareddy R, Ho J, Jiao Q, Harvilla P, et al. Bifunctional molecules targeting SARS-CoV-2 spike and the polymeric Ig receptor display neutralization activity and mucosal enrichment. MAbs. 2021;13:1987180 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Stampfer S, Goldwater M, Jew S, Bujarski S, Regidor B, Daniely D, et al. Response to mRNA vaccination for COVID-19 among patients with multiple myeloma. Leukemia. 2021;35:3534-3541 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Li D, Edwards R, Manne K, Martinez D, Schäfer A, Alam S, et al. In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies. Cell. 2021;184:4203-4219.e32 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Bohländer F, Riehl D, Weißmüller S, Gutscher M, Schüttrumpf J, Faust S. Immunomodulation: Immunoglobulin Preparations Suppress Hyperinflammation in a COVID-19 Model via FcγRIIA and FcαRI. Front Immunol. 2021;12:700429 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Heggestad J, Kinnamon D, Olson L, Liu J, Kelly G, Wall S, et al. Multiplexed, quantitative serological profiling of COVID-19 from blood by a point-of-care test. Sci Adv. 2021;7: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Williams W, Meyerhoff R, Edwards R, Li H, Manne K, Nicely N, et al. Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies. Cell. 2021;184:2955-2972.e25 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Si L, Bai H, Rodas M, Cao W, Oh C, Jiang A, et al. A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics. Nat Biomed Eng. 2021;5:815-829 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
DiMuzio J, Heimbach B, Howanski R, Dowling J, Patel N, Henriquez N, et al. Unbiased interrogation of memory B cells from convalescent COVID-19 patients reveals a broad antiviral humoral response targeting SARS-CoV-2 antigens beyond the spike protein. Vaccine X. 2021;8:100098 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Song D, Wang W, Dong C, Ning Z, Liu X, Liu C, et al. Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2. Commun Biol. 2021;4:500 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Akilesh S, Nicosia R, Alpers C, Tretiakova M, Hsiang T, Gale M, et al. Characterizing Viral Infection by Electron Microscopy: Lessons from the Coronavirus Disease 2019 Pandemic. Am J Pathol. 2021;191:222-227 pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Heggestad J, Kinnamon D, Olson L, Liu J, Kelly G, Wall S, et al. Multiplexed, quantitative serological profiling of COVID-19 from a drop of blood by a point-of-care test. medRxiv. 2020;: pubmed publisher
  • flow cytometry; SARS coronavirus
  • neutralization; SARS coronavirus
  • immunocytochemistry; SARS coronavirus
  • ELISA; SARS coronavirus
Acharya P, Williams W, Henderson R, Janowska K, Manne K, Parks R, et al. A glycan cluster on the SARS-CoV-2 spike ectodomain is recognized by Fab-dimerized glycan-reactive antibodies. bioRxiv. 2020;: pubmed publisher
Behbahanipour M, Benoit R, Navarro S, Ventura S. OligoBinders: Bioengineered Soluble Amyloid-like Nanoparticles to Bind and Neutralize SARS-CoV-2. ACS Appl Mater Interfaces. 2023;15:11444-11457 pubmed publisher
Ham Y, Cho N, Kim D, Kim J, Jo M, Jeong M, et al. The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction. Biosens Bioelectron. 2023;227:115169 pubmed publisher
Mortazavi M, Bains A, Afsah Hejri L, Ehsani R, LiWang P. SARS-CoV-2 pseudotyped virus persists on the surface of multiple produce but can be inactivated with gaseous ozone. Heliyon. 2022;8:e10280 pubmed publisher
image
image 1 :
Sino Biological 40150-D001 image 1
product information
Catalog Number :
40150-D001
Product Name :
SARS-CoV / SARS-CoV-2 Spike antibody, Chimeric MAb
Product Type :
Antibody
Host Species :
Chimera
Clonality :
monoclonal
Conjugation :
Unconjugated
Isotype :
mouse (variable region) / human (kappa / IgG1 constant)
Size :
100 µL
List Price :
400 USD
Gene ID :
D001
Product Description :
It is a chimeric monoclonal antibody combining the constant domains of the human IgG1 molecule with mouse variable regions. The variable region was obtained from a mouse immunized with purified, recombinant SARS-CoV Spike RBD Protein. The antibody was produced using recombinant antibody technology.
SpeciesSummary :
SARS
ALTnames :
Spike
Immunogen :
Recombinant SARS-CoV Spike RBD Protein (Catalog#40150-V08B2)
Purity :
protein A
Buffer :
50mM Hepes, 100mM NaCl, pH 8.0
Application Summary :
ELISA,FCM,ICC/IF,Neutralization
Storage :
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.