product summary
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company name :
Sino Biological
product type :
protein
product name :
MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297, His Tag)
catalog :
40069-V08B
quantity :
100 µg
price :
498 USD
more info or order :
citations: 23
Published Application/Species/Sample/DilutionReference
  • ELISA; MERS coronavirus
Ozharovskaia T, Zubkova O, Dolzhikova I, Gromova A, Grousova D, Tukhvatulin A, et al. Immunogenicity of Different Forms of Middle East Respiratory Syndrome S Glycoprotein. Acta Naturae. 2019;11:38-47 pubmed
  • ELISA; MERS coronavirus
Hashem A, Al Amri S, Al Subhi T, Siddiq L, Hassan A, Alawi M, et al. Development and validation of different indirect ELISAs for MERS-CoV serological testing. J Immunol Methods. 2019;466:41-46 pubmed publisher
  • ELISA; MERS coronavirus
Wang W, Wang H, Deng Y, Song T, Lan J, Wu G, et al. Characterization of anti-MERS-CoV antibodies against various recombinant structural antigens of MERS-CoV in an imported case in China. Emerg Microbes Infect. 2016;5:e113 pubmed publisher
Peng Y, Huang Y, Kiessling F, Renn D, Rueping M. Nanobody-Based Lateral Flow Immunoassay for Rapid Antigen Detection of SARS-CoV-2 and MERS-CoV Proteins. ACS Synth Biol. 2025;14:420-430 pubmed publisher
Tasi x107 N, Konjevi x107 I, Lobato A, Metarapi D, Fin x161 gar M, Oliveira F, et al. Study of V2CTx-MXene Based Immunosensor for Sensitive Label-Free Impedimetric Detection of SARS-CoV-2 Spike Protein. ACS Appl Mater Interfaces. 2024;16:30196-30208 pubmed publisher
Heo C, Lim W, Yang J, Son S, Kim S, Kim D, et al. Novel S2 subunit-specific antibody with broad neutralizing activity against SARS-CoV-2 variants of concern. Front Immunol. 2023;14:1307693 pubmed publisher
Zargartalebi H, Yousefi H, Flynn C, Gomis S, Das J, Young T, et al. Capillary-Assisted Molecular Pendulum Bioanalysis. J Am Chem Soc. 2022;144:18338-18349 pubmed publisher
Sun X, Yi C, Zhu Y, Ding L, Xia S, Chen X, et al. Neutralization mechanism of a human antibody with pan-coronavirus reactivity including SARS-CoV-2. Nat Microbiol. 2022;7:1063-1074 pubmed publisher
Chen Y, Tong P, WHITEMAN N, Moghaddam A, Zarghami M, Zuiani A, et al. Immune recall improves antibody durability and breadth to SARS-CoV-2 variants. Sci Immunol. 2022;:eabp8328 pubmed publisher
Geanes E, LeMaster C, Fraley E, Khanal S, McLennan R, Grundberg E, et al. Cross-reactive antibodies elicited to conserved epitopes on SARS-CoV-2 spike protein after infection and vaccination. Sci Rep. 2022;12:6496 pubmed publisher
Lai G, Chao T, Lin S, Kao H, Tsai Y, Lu D, et al. Neutralization or enhancement of SARS-CoV-2 infection by a monoclonal antibody targeting a specific epitope in the spike receptor-binding domain. Antiviral Res. 2022;200:105290 pubmed publisher
Li C, Chao T, Chang T, Hsiao C, Lu D, Chiang Y, et al. Neutralizing Monoclonal Antibodies Inhibit SARS-CoV-2 Infection through Blocking Membrane Fusion. Microbiol Spectr. 2022;10:e0181421 pubmed publisher
Li M, Liu J, Lu R, Zhang Y, Du M, Xing M, et al. Longitudinal immune profiling reveals dominant epitopes mediating long-term humoral immunity in COVID-19-convalescent individuals. J Allergy Clin Immunol. 2022;149:1225-1241 pubmed publisher
Cho H, Gonzales Wartz K, Huang D, Yuan M, Peterson M, Liang J, et al. Bispecific antibodies targeting distinct regions of the spike protein potently neutralize SARS-CoV-2 variants of concern. Sci Transl Med. 2021;13:eabj5413 pubmed publisher
Song D, Wang W, Dong C, Ning Z, Liu X, Liu C, et al. Structure and function analysis of a potent human neutralizing antibody CA521FALA against SARS-CoV-2. Commun Biol. 2021;4:500 pubmed publisher
Cho H, Gonzales Wartz K, Huang D, Yuan M, Peterson M, Liang J, et al. Ultrapotent bispecific antibodies neutralize emerging SARS-CoV-2 variants. bioRxiv. 2021;: pubmed publisher
Huang K, Tan T, Chen T, Huang C, Harvey R, Hussain S, et al. Breadth and function of antibody response to acute SARS-CoV-2 infection in humans. PLoS Pathog. 2021;17:e1009352 pubmed publisher
Dolzhikova I, Grousova D, Zubkova O, Tukhvatulin A, Kovyrshina A, Lubenets N, et al. Preclinical Studies of Immunogenity, Protectivity, and Safety of the Combined Vector Vaccine for Prevention of the Middle East Respiratory Syndrome. Acta Naturae. 2020;12:114-123 pubmed publisher
Kim S, Jin W, Sood A, Montgomery D, Grant O, Fuster M, et al. Characterization of heparin and severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) spike glycoprotein binding interactions. Antiviral Res. 2020;:104873 pubmed publisher
Fan C, Wu X, Liu Q, Li Q, Liu S, Lu J, et al. A Human DPP4-Knockin Mouse's Susceptibility to Infection by Authentic and Pseudotyped MERS-CoV. Viruses. 2018;10: pubmed publisher
Deng Y, Lan J, Bao L, Huang B, Ye F, Chen Y, et al. Enhanced protection in mice induced by immunization with inactivated whole viruses compare to spike protein of middle east respiratory syndrome coronavirus. Emerg Microbes Infect. 2018;7:60 pubmed publisher
Trivedi S, Miao C, Al Abdallat M, Haddadin A, Alqasrawi S, Iblan I, et al. Inclusion of MERS-spike protein ELISA in algorithm to determine serologic evidence of MERS-CoV infection. J Med Virol. 2018;90:367-371 pubmed publisher
Chiang H, Lin S. Polyamide-kieselguhr thin-layer chromatography of yellow food dyes. J Chromatogr. 1969;44:203-4 pubmed
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Sino Biological 40069-V08B image 1
product information
Catalog Number :
40069-V08B
Product Name :
MERS-CoV Spike Protein (S1+S2 ECD, aa 1-1297, His Tag)
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
C-His
Size :
100 µg
List Price :
498 USD
Gene ID :
AFS88936.1
Product Description :
A DNA sequence encoding the MERS-CoV extracellular domain of spike protein (AFS88936.1) (Met1-Trp1297) was fused with a polyhistidine tag at the C-terminus.
SpeciesSummary :
MERS-CoV
ALTnames :
Spike
Purity :
> 85 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile 20mM Tris, 300mM NaCl, 10% glycerol, pH7.5
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.