product summary
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company name :
Sino Biological
product type :
protein
product name :
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike/S1 Protein (S1 Subunit, His Tag)
catalog :
40021-V08H
quantity :
100 µg
price :
448 USD
more info or order :
Sino Biological product webpage
citations: 11
Reference
Zhang S, Xu C, Wang J, Xiong X, Wang J. Spike proteins of coronaviruses activate mast cells for degranulation via stimulating Src/PI3K/AKT/Ca2+ intracellular signaling cascade. J Virol. 2025;99:e0007825 pubmed publisher
Anderson E, Li S, Awofolaju M, Eilola T, Goodwin E, Bolton M, et al. SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations. Cell Rep. 2022;41:111496 pubmed publisher
Denninger V, Xu C, Meisl G, Morgunov A, Fiedler S, Ilsley A, et al. Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV-2. ACS Infect Dis. 2022;8:790-799 pubmed publisher
Sim K, Ko G, Bae S, Choi K, Lee J, Kim B, et al. Two Opposing Roles of SARS-CoV-2 RBD-Reactive Antibodies in Pre-Pandemic Plasma Samples From Elderly People in ACE2-Mediated Pseudovirus Infection. Front Immunol. 2021;12:813240 pubmed publisher
Egwang T, Owalla T, Okurut E, Apungia G, Fox A, De Carlo C, et al. Differential pre-pandemic breast milk IgA reactivity against SARS-CoV-2 and circulating human coronaviruses in Ugandan and American mothers. Int J Infect Dis. 2021;112:165-172 pubmed publisher
Longworth J, Dittmar G. An antigen microarray protocol for COVID-19 serological analysis. STAR Protoc. 2021;2:100815 pubmed publisher
Ravindran R, McReynolds C, Yang J, Hammock B, Ikram A, Ali A, et al. Immune response dynamics in COVID-19 patients to SARS-CoV-2 and other human coronaviruses. PLoS ONE. 2021;16:e0254367 pubmed publisher
Aydillo T, Rombauts A, Stadlbauer D, Aslam S, Abelenda Alonso G, Escalera A, et al. Immunological imprinting of the antibody response in COVID-19 patients. Nat Commun. 2021;12:3781 pubmed publisher
Bertoglio F, Meier D, Langreder N, Steinke S, Rand U, Simonelli L, et al. SARS-CoV-2 neutralizing human recombinant antibodies selected from pre-pandemic healthy donors binding at RBD-ACE2 interface. Nat Commun. 2021;12:1577 pubmed publisher
Pierce C, Preston Hurlburt P, Dai Y, Aschner C, Cheshenko N, Galen B, et al. Immune responses to SARS-CoV-2 infection in hospitalized pediatric and adult patients. Sci Transl Med. 2020;12: pubmed publisher
Al Kahlout R, Nasrallah G, Farag E, Wang L, Lattwein E, Muller M, et al. Comparative Serological Study for the Prevalence of Anti-MERS Coronavirus Antibodies in High- and Low-Risk Groups in Qatar. J Immunol Res. 2019;2019:1386740 pubmed publisher
image
image 1 :
Sino Biological 40021-V08H image 1
product information
Catalog Number :
40021-V08H
Product Name :
Human coronavirus HKU1 (isolate N1) (HCoV-HKU1) Spike/S1 Protein (S1 Subunit, His Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-His
Size :
100 µg
List Price :
448 USD
Gene ID :
YP_173238.1
Product Description :
A DNA sequence encoding the human coronavirus HKU1 (isolate N1) (HCoV-HKU1) spike protein (S1 Subunit) (YP_173238.1) (Met 1-Arg 760) was expressed with a polyhistidine tag at the C-terminus.
SpeciesSummary :
HCoV-HKU1
ALTnames :
Spike
Purity :
> 90 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.