protein

Human CCR5-Detergent Protein (Flag & His-Strep Tag, thermostabilizing mutations)

13022-H82H-DD

100 µg

1048 USD

Human CCR5-Detergent Protein (Flag & His-Strep Tag, thermostabilizing mutations)

Protein

HEK293 Cells

N-Flag & C-His-Strep

100 µg

1048 USD

P51681

A DNA sequence encoding the Human CCR5-Detergent (P51681)(Met1-Arg319) was expressed, with a Flag tag at the N-terminus, a polyhistidine tag and a strep tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our detergent platform. The transmembrane proteins' hydrophobic regions pose a challenge in maintaining their native conformation post-extraction from cellular membranes in standard buffers. To address this, our detergent technology platform utilizes a traditional yet proven membrane protein extraction method, incorporating detergents to stabilize the proteins. This method efficiently produces highly purified membrane protein products, suitable for use in early drug screening and research applications.

Human

CCCKR5,CC-CKR-5,CCR-5,CD195,CKR5,CKR-5,CMKBR5,IDDM22,CCR5

≥ 90 % as determined by SDS-PAGE.

Supplied as sterile 50 mM HEPES, 150 mM NaCl, 0.02% DDM, 0.004% CHS, 5% Glycerol, pH 7.5.

It is supplied and shipped as liquid with dry ice.

Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.