Human C6 / complement component 6 Protein (His Tag) | Sino Biological 12426-H08H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human C6 / complement component 6 Protein (His Tag)

catalog :

12426-H08H

quantity :

100 µg

price :

138 USD

more info or order :

Sino Biological product webpage

citations: 8

Reference
Wu Z, Zhang Z, Zhou S, Xie M, Liu L, Luo C, et al. ERK1/2-dependent activity of SOX9 is required for sublytic C5b-9-induced expression of FGF1, PDGFα, and TGF-β1 in rat Thy-1 nephritis. Int Immunopharmacol. 2024;127:111372 pubmed publisher
Wang W, Qian B, Zhao C, Peng M, Liu L, Xie M, et al. Sublytic C5b-9 Induces CCL3/4 Production and Macrophage Accumulation in Thy-1N Rats via PKC-α/p65/IRF-8 Axis. Int J Biol Sci. 2022;18:3178-3193 pubmed publisher
Xie M, Wu Z, Ying S, Liu L, Zhao C, Yao C, et al. Sublytic C5b-9 induces glomerular mesangial cell proliferation via ERK1/2-dependent SOX9 phosphorylation and acetylation by enhancing Cyclin D1 in rat Thy-1 nephritis. Exp Mol Med. 2021;53:572-590 pubmed publisher
Yu T, Wang L, Zhao C, Qian B, Yao C, He F, et al. Sublytic C5b-9 induces proliferation of glomerular mesangial cells via ERK5/MZF1/RGC-32 axis activated by FBXO28-TRAF6 complex. J Cell Mol Med. 2019;23:5654-5671 pubmed publisher
Yao C, He F, Liu L, Zhang Z, Zhao C, Qiu W, et al. Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis Through miR-3546/SOX4/Survivin Axis in Rat Thy-1 Nephritis. Cell Physiol Biochem. 2018;49:1898-1917 pubmed publisher
Zhu G, Qiu W, Li Y, Zhao C, He F, Zhou M, et al. Sublytic C5b-9 Induces Glomerular Mesangial Cell Apoptosis through the Cascade Pathway of MEKK2-p38 MAPK-IRF-1-TRADD-Caspase 8 in Rat Thy-1 Nephritis. J Immunol. 2017;198:1104-1118 pubmed publisher
He F, Zhou M, Yu T, Zhao D, Zhang J, Qiu W, et al. Sublytic C5b-9 triggers glomerular mesangial cell apoptosis in rat Thy-1 nephritis via Gadd45 activation mediated by Egr-1 and p300-dependent ATF3 acetylation. J Mol Cell Biol. 2016;8:477-491 pubmed
Zhang J, Li Y, Shan K, Wang L, Qiu W, Lu Y, et al. Sublytic C5b-9 induces IL-6 and TGF-?1 production by glomerular mesangial cells in rat Thy-1 nephritis through p300-mediated C/EBP? acetylation. FASEB J. 2014;28:1511-25 pubmed publisher

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product information

Catalog Number :

12426-H08H

Product Name :

Human C6 / complement component 6 Protein (His Tag)

Product Type :

Protein

Host Species :

HEK293 Cells

Conjugation :

C-His

Size :

100 µg

List Price :

138 USD

Gene ID :

AAA59668.1

Product Description :

A DNA sequence encoding the human C6 (AAA59668.1) (Met 1-Ala 934) was fused with a polyhistidine tag at the C-terminus.

SpeciesSummary :

Human

ALTnames :

Purity :

> 90 % as determined by SDS-PAGE

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage