protein

Human CCR7/CD197 Protein (Nanodisc, Flag-His & Strep Tag)

12112-H95H-NA

100 µg

4198 USD

Human CCR7/CD197 Protein (Nanodisc, Flag-His & Strep Tag)

Protein

HEK293 Cells

N-Flag-His & C-Strep

100 µg

4198 USD

P32248

A DNA sequence encoding the Human CCR7 (P32248) (Gln25-Gln252 & Glu257-Leu344, FP2, thermostabilizing mutations) was expressed, with a polyhistidine tag and Flag tag at the N-terminus, and a strep tag at the C-terminus. Within the expressed regions, there are several proprietary thermostabilizing mutations.This protein was prepared using our Nanodisc platform. Nanodisc is a versatile tool for studying membrane proteins. Using styrene-maleic acid (SMA) copolymer, membrane proteins can be extracted directly from prokaryotic and eukaryotic expression systems in the absence of detergents to preserve the protein structure and function better. Compared to membrane scaffold proteins (MSPs) nanodiscs, SMA nanodiscs also have the advantage of preserving proteins' nature by maintaining native lipids surrounded without introducing any heterologous proteins, which allows studies of protein structure and functions in a native-like environment.

Human

BLR2,CC-CKR-7,CCR-7,CD197,CDw197,CMKBR7,EBI1,EVI1

≥ 85 % as determined by SDS-PAGE.

Supplied as sterile 50 mM HEPES, 150 mM NaCl, pH 7.5.

It is supplied and shipped as liquid with dry ice.

Samples are stable for up to twelve months from date of receipt at -70℃. Store it under sterile conditions at -70℃ or lower. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.