product summary
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company name :
Sino Biological
product type :
protein
product name :
Human KEAP1 / INRF2 Protein
catalog :
11981-HNCB
quantity :
100 µg
price :
298 USD
more info or order :
Sino Biological product webpage
citations: 9
Reference
Liao Z, Zhou W, Du S, Liu X, Yao J, Din Z, et al. Licochalcone B alleviates atherosclerosis by inhibiting endothelial inflammation via targeting the KEAP1/NRF2/NF-κB signalling pathway. Phytomedicine. 2026;157:158333 pubmed publisher
Zhang Y, Lin D, Yao X, Dai F, Wang Q, Zhou B. Identification and mechanistic exploration of a mono-carbonyl analog A1 of dietary curcumin as a potent Nrf2-dependent neuroprotective agent within a cellular model of Parkinson's disease. Free Radic Biol Med. 2026;244:174-185 pubmed publisher
Fath J, Brouillard F, Claverie D, Cabay xe9 A, Nuss P, Chwetzoff S, et al. BDNF exerts an NRF2-dependent cytoprotective function via a receptor-independent pathway. Cell Rep. 2025;44:116587 pubmed publisher
Guo R, Quan S, Yan X, Jia Y, Wang N, Bu J, et al. Atractylenolide III alleviates cerebral ischemia-reperfusion injury by targeting Keap1 to activate the Nrf2/HO-1 pathway. Phytomedicine. 2025;148:157284 pubmed publisher
Shi N, Wang J, Su G, Ma G, Huang F, Jin S, et al. N -Acetyl-Tryptophan in Acute Kidney Injury after Cardiac Surgery. J Am Soc Nephrol. 2025;36:1040-1055 pubmed publisher
Payne N, Maksoud S, Tannous B, Mazitschek R. A direct high-throughput protein quantification strategy facilitates discovery and characterization of a celastrol-derived BRD4 degrader. Cell Chem Biol. 2022;29:1333-1340.e5 pubmed publisher
Dai Z, An L, Chen X, Yang F, Zhao N, Li C, et al. Target Fishing Reveals a Novel Mechanism of 1,2,4-Oxadiazole Derivatives Targeting Rpn6, a Subunit of 26S Proteasome. J Med Chem. 2022;65:5029-5043 pubmed publisher
Payne N, Kalyakina A, Singh K, Tye M, Mazitschek R. Bright and stable luminescent probes for target engagement profiling in live cells. Nat Chem Biol. 2021;17:1168-1177 pubmed publisher
Hayashi M, Guida E, Inokawa Y, Goldberg R, Reis L, Ooki A, et al. GULP1 regulates the NRF2-KEAP1 signaling axis in urothelial carcinoma. Sci Signal. 2020;13: pubmed publisher
image
image 1 :
Sino Biological 11981-HNCB image 1
product information
Catalog Number :
11981-HNCB
Product Name :
Human KEAP1 / INRF2 Protein
Product Type :
Protein
Host Species :
Baculovirus-Insect Cells
Conjugation :
N-cleavage
Size :
100 µg
List Price :
298 USD
Gene ID :
9817
Product Description :
A DNA sequence encoding the human KEAP1 (Q14145) (Gln2-Cys624) was expressed and purified with two additional amino acids (Gly & Pro ) at the N-terminus.
SpeciesSummary :
Human
ALTnames :
KEAP1,INrf2,KLHL19,KIAA0132,MGC10630,MGC1114,MGC20887,MGC4407,MGC9454
Purity :
≥ 85 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile 20mM Tris, 300 mM NaCl, 10% Glycerol, 1 mM TCEP, pH 7.5.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.