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company name :
Sino Biological
product type :
protein
product name :
Human IFN-gamma / IFNG / γ-IFN Protein
catalog :
11725-HNAS
quantity :
1 mg
price :
898 USD
more info or order :
Sino Biological product webpage
citations: 21
Reference
He X, Liu Y, Gao X, Tang F, Tian Y, Gong S, et al. N-terminal acetylation of transcription factor LIP induces immune therapy resistance via suppression of PD-L1 expression in non-small cell lung cancer. J Immunother Cancer. 2024;12: pubmed publisher
Lu P, Cheng Y, Xue L, Ren X, Xu X, Chen C, et al. Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell. 2024;187:7126-7142.e20 pubmed publisher
Zhong P, Nakata K, Oyama K, Higashijima N, Sagara A, Date S, et al. Blockade of histamine receptor H1 augments immune checkpoint therapy by enhancing MHC-I expression in pancreatic cancer cells. J Exp Clin Cancer Res. 2024;43:138 pubmed publisher
Deng B, Wang J, Yang T, Deng Z, Yuan J, Zhang B, et al. TNF and IFNγ-induced cell death requires IRF1 and ELAVL1 to promote CASP8 expression. J Cell Biol. 2024;223: pubmed publisher
Heo H, Park H, Lee M, Kim J, Kim J, Jung S, et al. TRIM22 facilitates autophagosome-lysosome fusion by mediating the association of GABARAPs and PLEKHM1. Autophagy. 2023;:1-16 pubmed publisher
Tang F, Lu C, He X, Lin W, Xie B, Gao X, et al. E3 ligase Trim35 inhibits LSD1 demethylase activity through K63-linked ubiquitination and enhances anti-tumor immunity in NSCLC. Cell Rep. 2023;42:113477 pubmed publisher
Miao Z, Ran J, Mou D, Wu S, Chen Y, Li C, et al. [YKL-40 Promotes the Expression of Inflammatory Factors in Type Ⅱ Alveolar Epithelial Cell Model of A549 Cell Line]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2023;54:954-958 pubmed publisher
Xiao D, Zeng T, Zhu W, Yu Z, Huang W, Yi H, et al. ANXA1 Promotes Tumor Immune Evasion by Binding PARP1 and Upregulating Stat3-Induced Expression of PD-L1 in Multiple Cancers. Cancer Immunol Res. 2023;11:1367-1383 pubmed publisher
Chen X, Gao Y, Xie J, Hua H, Pan C, Huang J, et al. Identification of FCN1 as a novel macrophage infiltration-associated biomarker for diagnosis of pediatric inflammatory bowel diseases. J Transl Med. 2023;21:203 pubmed publisher
Tang X, Sui X, Liu Y. Immune checkpoint PTPN2 predicts prognosis and immunotherapy response in human cancers. Heliyon. 2023;9:e12873 pubmed publisher
Liu L, Shi W, Xiao X, Wu X, Hu H, Yuan S, et al. BCG immunotherapy inhibits cancer progression by promoting the M1 macrophage differentiation of THP‑1 cells via the Rb/E2F1 pathway in cervical carcinoma. Oncol Rep. 2021;46: pubmed publisher
Yang C, Chang M, Chang C, Shyur L. Phytogalactolipid dLGG Inhibits Mouse Melanoma Brain Metastasis through Regulating Oxylipin Activity and Re-Programming Macrophage Polarity in the Tumor Microenvironment. Cancers (Basel). 2021;13: pubmed publisher
Shang M, Yang H, Yang R, Chen T, Fu Y, Li Y, et al. The folate cycle enzyme MTHFD2 induces cancer immune evasion through PD-L1 up-regulation. Nat Commun. 2021;12:1940 pubmed publisher
Fan W, Song Y, Ren Z, Cheng X, Li P, Song H, et al. Glioma cells are resistant to inflammation‑induced alterations of mitochondrial dynamics. Int J Oncol. 2020;57:1293-1306 pubmed publisher
Wei M, Fan X, Ding M, Li R, Shao S, Hou Y, et al. Nuclear actin regulates inducible transcription by enhancing RNA polymerase II clustering. Sci Adv. 2020;6:eaay6515 pubmed publisher
Xu Y, Wu Y, Zhang S, Ma P, Jin X, Wang Z, et al. A Tumor-Specific Super-Enhancer Drives Immune Evasion by Guiding Synchronous Expression of PD-L1 and PD-L2. Cell Rep. 2019;29:3435-3447.e4 pubmed publisher
Wang H, Yan Z, Hao J, Yang B, Wang J, Yi L, et al. CD137 ligand feedback upregulates PD-L1 expression on lung cancer via T cell production of IFN-γ. Thorac Cancer. 2019;10:2225-2235 pubmed publisher
Huang R, Wu J, Zhou X, Jiang H, Guoying Zhou G, Roizman B. Herpes Simplex Virus 1 MicroRNA miR-H28 Exported to Uninfected Cells in Exosomes Restricts Cell-to-Cell Virus Spread by Inducing Gamma Interferon mRNA. J Virol. 2019;93: pubmed publisher
Kim J, Yang J, Kim Y, Lee H, Kim S, Poo H. Development of a Specific CHIKV-E2 Monoclonal Antibody for Chikungunya Diagnosis. Virol Sin. 2019;: pubmed publisher
Gordón Alonso M, Hirsch T, Wildmann C, van der Bruggen P. Galectin-3 captures interferon-gamma in the tumor matrix reducing chemokine gradient production and T-cell tumor infiltration. Nat Commun. 2017;8:793 pubmed publisher
Skehan M, McKenna P. Sarcoidosis of the endometrium: a case presentation. Ir J Med Sci. 1985;154:114 pubmed
image
image 1 :
Sino Biological 11725-HNAS image 1
product information
Catalog Number :
11725-HNAS
Product Name :
Human IFN-gamma / IFNG / γ-IFN Protein
Product Type :
Protein
Host Species :
CHO Stable Cells
Conjugation :
Native
Size :
1 mg
List Price :
898 USD
Gene ID :
NP_000610.2
Product Description :
A DNA sequence encoding the human γ-IFN (NP_000610.2) (Met 1-Gln 166) was expressed and purified.
SpeciesSummary :
Human
ALTnames :
IFG,IFI,IMD69
Purity :
> 92 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
Sino Biological product webpage
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.