Human Progranulin Protein (His Tag) | Sino Biological 10826-H08H product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human Progranulin Protein (His Tag)

catalog :

10826-H08H

quantity :

1 mg

price :

2248 USD

more info or order :

Sino Biological product webpage

citations: 9

Published Application/Species/Sample/Dilution	Reference
ELISA; human	Suarez Calvet M, Capell A, Araque Caballero M, Morenas Rodríguez E, Fellerer K, Franzmeier N, et al. CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline. EMBO Mol Med. 2018;10: pubmed publisher
	Leighton P, Ching K, Reynolds K, Vuong C, Zeng B, Zhang Y, et al. Chickens with a Truncated Light Chain Transgene Express Single-Domain H Chain-Only Antibodies. J Immunol. 2024;212:1744-1753 pubmed publisher
	Ching K, Berg K, Reynolds K, Pedersen D, Macias A, Abdiche Y, et al. Common light chain chickens produce human antibodies of high affinity and broad epitope coverage for the engineering of bispecifics. MAbs. 2021;13:1862451 pubmed publisher
	Liu L, Guo H, Song A, Huang J, Zhang Y, Jin S, et al. Progranulin inhibits LPS-induced macrophage M1 polarization via NF-кB and MAPK pathways. BMC Immunol. 2020;21:32 pubmed publisher
	Ching K, Berg K, Morales J, Pedersen D, Harriman W, Abdiche Y, et al. Expression of human lambda expands the repertoire of OmniChickens. PLoS ONE. 2020;15:e0228164 pubmed publisher
	Chen Q, Cai J, Li X, Song A, Guo H, Sun Q, et al. Progranulin Promotes Regeneration of Inflammatory Periodontal Bone Defect in Rats via Anti-inflammation, Osteoclastogenic Inhibition, and Osteogenic Promotion. Inflammation. 2019;42:221-234 pubmed publisher
	Ching K, COLLARINI E, Abdiche Y, Bedinger D, Pedersen D, Izquierdo S, et al. Chickens with humanized immunoglobulin genes generate antibodies with high affinity and broad epitope coverage to conserved targets. MAbs. 2017;:1-10 pubmed publisher
	Wang L, Yang D, Tian J, Gao A, Shen Y, Ren X, et al. Tumor necrosis factor receptor 2/AKT and ERK signaling pathways contribute to the switch from fibroblasts to CAFs by progranulin in microenvironment of colorectal cancer. Oncotarget. 2017;8:26323-26333 pubmed publisher
	Abdiche Y, Harriman R, Deng X, Yeung Y, Miles A, Morishige W, et al. Assessing kinetic and epitopic diversity across orthogonal monoclonal antibody generation platforms. MAbs. 2016;8:264-77 pubmed publisher

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product information

Catalog Number :

10826-H08H

Product Name :

Human Progranulin Protein (His Tag)

Product Type :

Protein

Host Species :

HEK293 Cells

Conjugation :

C-His

Size :

1 mg

List Price :

2248 USD

Gene ID :

NP_002078.1

Product Description :

A DNA sequence encoding the human Progranulin (NP_002078.1) (Met 1-Leu 593) with a C-terminal polyhistidine tag was expressed.

SpeciesSummary :

Human

ALTnames :

CLN11,GEP,GP88,PCDGF,PEPI,PGRN

Purity :

> 95 % as determined by SDS-PAGE

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage