This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Sino Biological
product type :
protein
product name :
Human IL-35 (IL12A & EBI3 Heterodimer) Protein (Fc Tag)
catalog :
10705-H02H
quantity :
Please Inquire
price :
Please Inquire
citations: 5
Reference
Abdi E, Najafipour H, Joukar S, Dabiri S, Esmaeli Mahani S, Abbasloo E, et al. Expression of IGF-1, IL-27 and IL-35 Receptors in Adjuvant Induced Rheumatoid Arthritis Model. Iran J Immunol. 2018;15:14-27 pubmed publisher
Wang Y, Mao Y, Zhang J, Shi G, Cheng L, Lin Y, et al. IL-35 recombinant protein reverses inflammatory bowel disease and psoriasis through regulation of inflammatory cytokines and immune cells. J Cell Mol Med. 2018;22:1014-1025 pubmed publisher
Yu W, Ge M, Lu S, Shi J, Li X, Zhang J, et al. Anti-inflammatory effects of interleukin-35 in acquired aplastic anemia. Cytokine. 2015;76:409-416 pubmed publisher
Sun T, Zhang D, Yang Y, Zhang X, Lv C, Fu R, et al. Interleukin 35 may contribute to the loss of immunological self-tolerance in patients with primary immune thrombocytopenia. Br J Haematol. 2015;169:278-85 pubmed publisher
Zhang X, Zhou Y, Xu L, Han W, Chen H, Chen Y, et al. Reduced IL-35 levels are associated with increased platelet aggregation and activation in patients with acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation. Ann Hematol. 2015;94:837-45 pubmed publisher
product information
Catalog Number :
10705-H02H
Product Name :
Human IL-35 (IL12A & EBI3 Heterodimer) Protein (Fc Tag)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
C-human IgG1-Fc
Size :
Please Inquire
List Price :
Please Inquire
Gene ID :
NP_005746.2 & P29459
Product Description :
A DNA sequence encoding the human IL35 complex composed of IL27B subunit (NP_005746.2) (Met 1-Lys 229) and the mature form of human IL12 p35 subunit (P29459) (Arg 23-Ser 219) linked by a polypeptide linker was fused with the Fc region of human IgG1 at the C-terminus.
SpeciesSummary :
Human
ALTnames :
IL12A & IL27B
Purity :
> 85 % as determined by SDS-PAGE
Buffer :
Lyophilized from sterile PBS, pH 7.4
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.