product summary
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company name :
Sino Biological
product type :
protein
product name :
Human IgG1-Fc Protein (103 Cys/Ser)
catalog :
10702-HNAH
quantity :
1 mg
price :
588 USD
more info or order :
citations: 16
Reference
Park J, Choi H, Jung K, Lee K, Shim J, Park K, et al. Production of recombinant human IgG1 Fc with beneficial N-glycosylation pattern for anti-inflammatory activity using genome-edited chickens. Commun Biol. 2023;6:589 pubmed publisher
Marshall M, Knaupp A, Spick C, Koese I, Maier M, Cragg M, et al. Development of C1q Affinity Chromatography for the Study of C1q-IgG Interactions. J Immunol. 2023;210:1837-1848 pubmed publisher
Xu Y, Viswanatha R, Sitsel O, Roderer D, Zhao H, Ashwood C, et al. CRISPR screens in Drosophila cells identify Vsg as a Tc toxin receptor. Nature. 2022;610:349-355 pubmed publisher
Swaminathan B, Youn S, Naiche L, Du J, Villa S, Metz J, et al. Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration. Sci Rep. 2022;12:1655 pubmed publisher
Li J, Xie R, Jiang F, Li Y, Zhu Y, Liu Z, et al. Tumor necrosis factor ligand-related molecule 1A maintains blood-retinal barrier via modulating SHP-1-Src-VE-cadherin signaling in diabetic retinopathy. FASEB J. 2021;35:e22008 pubmed publisher
Zhao Y, Lee C, Lin C, Gassen R, Xu X, Huang Z, et al. PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways. Immunity. 2019;51:1059-1073.e9 pubmed publisher
Buono M, Thézenas M, Ceroni A, Fischer R, Nerlov C. Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion. Nat Commun. 2018;9:4685 pubmed publisher
Mansouri S, Patel S, Katikaneni D, Blaauboer S, Wang W, Schattgen S, et al. Immature lung TNFR2- conventional DC 2 subpopulation activates moDCs to promote cyclic di-GMP mucosal adjuvant responses in vivo. Mucosal Immunol. 2019;12:277-289 pubmed publisher
Pardi N, Hogan M, Naradikian M, Parkhouse K, Cain D, Jones L, et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J Exp Med. 2018;215:1571-1588 pubmed publisher
Chen J, Luo Y, Hui H, Cai T, Huang H, Yang F, et al. CD146 coordinates brain endothelial cell-pericyte communication for blood-brain barrier development. Proc Natl Acad Sci U S A. 2017;114:E7622-E7631 pubmed publisher
Gao Q, Zhang J, Wang X, Liu Y, He R, Liu X, et al. The signalling receptor MCAM coordinates apical-basal polarity and planar cell polarity during morphogenesis. Nat Commun. 2017;8:15279 pubmed publisher
Zhang J, Jiang Z, Liu X, Meng A. Eph/ephrin signaling maintains the boundary of dorsal forerunner cell cluster during morphogenesis of the zebrafish embryonic left-right organizer. Development. 2016;143:2603-15 pubmed publisher
Liu L, Yu H, Huang X, Tan H, Li S, Luo Y, et al. A novel engineered VEGF blocker with an excellent pharmacokinetic profile and robust anti-tumor activity. BMC Cancer. 2015;15:170 pubmed publisher
Kashiwakura Y, Sakurai D, Kanno Y, Hashiguchi M, Kobayashi A, Kurosu A, et al. CD2-mediated regulation of peripheral CD4(+)  CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim. Immunology. 2013;139:48-60 pubmed publisher
Quadrato G, Benevento M, Alber S, Jacob C, Floriddia E, Nguyen T, et al. Nuclear factor of activated T cells (NFATc4) is required for BDNF-dependent survival of adult-born neurons and spatial memory formation in the hippocampus. Proc Natl Acad Sci U S A. 2012;109:E1499-508 pubmed publisher
Dai Y, Chen H, Mo C, Cui L, He W. Ectopically expressed human tumor biomarker MutS homologue 2 is a novel endogenous ligand that is recognized by human ?? T cells to induce innate anti-tumor/virus immunity. J Biol Chem. 2012;287:16812-9 pubmed publisher
image
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Sino Biological 10702-HNAH image 1
product information
Catalog Number :
10702-HNAH
Product Name :
Human IgG1-Fc Protein (103 Cys/Ser)
Product Type :
Protein
Host Species :
HEK293 Cells
Conjugation :
Native
Size :
1 mg
List Price :
588 USD
Gene ID :
P01857-1
Product Description :
A DNA sequence encoding the human IgG1 Fc region (P01857-1) (Glu99-Lys330) (one aa mutation, 103 Cys/Ser) was expressed.
SpeciesSummary :
Human
ALTnames :
IgG1-Fc
Purity :
≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
Buffer :
Lyophilized from sterile PBS, pH 7.4.
Packaging :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Storage :
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
more info or order :
company information
Sino Biological
Building 9, No.18 Kechuang 10th St, BDA, Beijing, 100176
marketing@sinobiological.com
https://www.sinobiological.com
86 400-890-9989
headquarters: China
Sino Biological is an international reagent supplier and service provider. The company specializes in recombinant protein production and antibody development. All of Sino Biological's products are independently developed and produced, including recombinant proteins, antibodies and cDNA clones. Sino Biological is the researchers' one-stop technical services shop for the advanced technology platforms they need to make advancements. In addition, Sino Biological offer pharmaceutical companies and biotechnology firms pre-clinical production technology services for hundreds of monoclonal antibody drug candidates.