Human C5a / Complement 5a Protein | Sino Biological 10604-HNAE product information

product summary

company name :

Sino Biological

product type :

protein

product name :

Human C5a / Complement 5a Protein

catalog :

10604-HNAE

quantity :

1 mg

price :

2268 USD

more info or order :

Sino Biological product webpage

citations: 8

Reference
Li X, Woodruff T. Protocol for cell-based screening assay to measure ERK1/2 phosphorylation as a readout for complement receptor activation. STAR Protoc. 2023;4:102758 pubmed publisher
Pandey S, Kumari P, Baidya M, Kise R, Cao Y, Dwivedi Agnihotri H, et al. Intrinsic bias at non-canonical, β-arrestin-coupled seven transmembrane receptors. Mol Cell. 2021;81:4605-4621.e11 pubmed publisher
Serfecz J, Saadin A, Santiago C, Zhang Y, Bentzen S, Vogel S, et al. C5a Activates a Pro-Inflammatory Gene Expression Profile in Human Gaucher iPSC-Derived Macrophages. Int J Mol Sci. 2021;22: pubmed publisher
Sullivan G, Galdi P, Borbye Lorenzen N, Stoye D, Lamb G, Evans M, et al. Preterm Birth Is Associated With Immune Dysregulation Which Persists in Infants Exposed to Histologic Chorioamnionitis. Front Immunol. 2021;12:722489 pubmed publisher
Sullivan G, Galdi P, Cabez M, Borbye Lorenzen N, Stoye D, Lamb G, et al. Interleukin-8 dysregulation is implicated in brain dysmaturation following preterm birth. Brain Behav Immun. 2020;90:311-318 pubmed publisher
Hoogendijk A, Pourfarzad F, Aarts C, Tool A, Hiemstra I, Grassi L, et al. Dynamic Transcriptome-Proteome Correlation Networks Reveal Human Myeloid Differentiation and Neutrophil-Specific Programming. Cell Rep. 2019;29:2505-2519.e4 pubmed publisher
Seow V, Lim J, Cotterell A, Yau M, Xu W, Lohman R, et al. Receptor residence time trumps drug-likeness and oral bioavailability in determining efficacy of complement C5a antagonists. Sci Rep. 2016;6:24575 pubmed publisher
Seow V, Lim J, Iyer A, Suen J, Ariffin J, Hohenhaus D, et al. Inflammatory responses induced by lipopolysaccharide are amplified in primary human monocytes but suppressed in macrophages by complement protein C5a. J Immunol. 2013;191:4308-16 pubmed publisher

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product information

Catalog Number :

10604-HNAE

Product Name :

Human C5a / Complement 5a Protein

Product Type :

Protein

Host Species :

E. coli

Conjugation :

Native

Size :

1 mg

List Price :

2268 USD

Gene ID :

NP_001726.2

Product Description :

A DNA sequence encoding the active form of human C5a (NP_001726.2) (Leu679-Arg751) was expressed.

SpeciesSummary :

Human

ALTnames :

C5a,C5b,C5D,CPAMD4,ECLZB

Purity :

> 94 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.

Buffer :

Lyophilized from sterile PBS, pH 7.4.

Packaging :

In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.

Storage :

Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

more info or order :

Sino Biological product webpage